Document Detail


The effects of clonidine premedication on the blood pressure and tachycardiac responses to ephedrine in elderly and young patients during propofol anesthesia.
MedLine Citation:
PMID:  12505939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
IMPLICATIONS: Clonidine premedication augments the pressor and tachycardiac responses to ephedrine in elderly patients during standard or large doses of propofol anesthesia but does not augment during small doses of propofol anesthesia. Clonidine, age, and propofol could be involved in the augmentation of the pressor and tachycardiac responses to ephedrine.
Authors:
Tadahiko Ishiyama; Satoshi Kashimoto; Takeshi Oguchi; Takashi Matsukawa; Teruo Kumazawa
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  96     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-12-30     Completed Date:  2003-01-21     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-41, table of contents     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesiology, Yamanashi Medical University, Japan. ishiyama@res.yamanashi-med.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adjuvants, Anesthesia / pharmacology
Adrenergic alpha-Agonists / pharmacology*
Adult
Aged
Aging / physiology*
Anesthesia, Intravenous*
Anesthetics, Intravenous*
Blood Pressure / drug effects*
Clonidine / pharmacology*
Double-Blind Method
Ephedrine / pharmacology*
Female
Heart Rate / drug effects*
Humans
Male
Midazolam / pharmacology
Middle Aged
Oxygen / blood
Preanesthetic Medication*
Propofol*
Tachycardia / chemically induced*
Chemical
Reg. No./Substance:
0/Adjuvants, Anesthesia; 0/Adrenergic alpha-Agonists; 0/Anesthetics, Intravenous; 2078-54-8/Propofol; 299-42-3/Ephedrine; 4205-90-7/Clonidine; 59467-70-8/Midazolam; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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