Document Detail

The effects of clonidine premedication on the blood pressure and tachycardiac responses to ephedrine in elderly and young patients during propofol anesthesia.
MedLine Citation:
PMID:  12505939     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: Clonidine premedication augments the pressor and tachycardiac responses to ephedrine in elderly patients during standard or large doses of propofol anesthesia but does not augment during small doses of propofol anesthesia. Clonidine, age, and propofol could be involved in the augmentation of the pressor and tachycardiac responses to ephedrine.
Tadahiko Ishiyama; Satoshi Kashimoto; Takeshi Oguchi; Takashi Matsukawa; Teruo Kumazawa
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  96     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-12-30     Completed Date:  2003-01-21     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-41, table of contents     Citation Subset:  AIM; IM    
Department of Anesthesiology, Yamanashi Medical University, Japan.
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MeSH Terms
Adjuvants, Anesthesia / pharmacology
Adrenergic alpha-Agonists / pharmacology*
Aging / physiology*
Anesthesia, Intravenous*
Anesthetics, Intravenous*
Blood Pressure / drug effects*
Clonidine / pharmacology*
Double-Blind Method
Ephedrine / pharmacology*
Heart Rate / drug effects*
Midazolam / pharmacology
Middle Aged
Oxygen / blood
Preanesthetic Medication*
Tachycardia / chemically induced*
Reg. No./Substance:
0/Adjuvants, Anesthesia; 0/Adrenergic alpha-Agonists; 0/Anesthetics, Intravenous; 2078-54-8/Propofol; 299-42-3/Ephedrine; 4205-90-7/Clonidine; 59467-70-8/Midazolam; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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