Document Detail


The effects of choline supplementation on physical performance.
MedLine Citation:
PMID:  10861337     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It has been reported that plasma choline levels decrease following certain types of strenuous exercise. Preliminary findings also suggest that a drop in plasma choline may limit physical performance, while choline supplementation may delay fatigue during prolonged efforts. A double-blind crossover design was used to determine the relationship between plasma choline and performance during and after 4 hr of strenuous exercise. Volunteers (N = 14) received either a placebo or treatment beverage (8.425 g choline citrate) prior to and midway through a 4-hr load carriage treadmill exercise (3% grade at 5.6 km/h 3 20 km) carrying a total load of 34.1 kg. Following the treadmill test, run time-to-exhaustion and squat tests were performed, and perceived exertion, plasma choline, glycerophosphocholine, and phosphatidylcholine were measured. Plasma choline levels increased 128% after the run-to-exhaustion with the choline supplemented beverage but remained unchanged with the placebo beverage. No significant effects were seen with choline supplementation on any outcome performance measure. Consequently, soldiers conditioned to carry heavy loads over long distances do not deplete plasma choline as a result of a prolonged exhaustive exercise under a placebo beverage, nor do they benefit from choline supplementation to delay fatigue under the same conditions.
Authors:
J P Warber; J F Patton; W J Tharion; S H Zeisel; R P Mello; C P Kemnitz; H R Lieberman
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  10     ISSN:  1526-484X     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-08-01     Completed Date:  2000-08-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  170-81     Citation Subset:  IM    
Affiliation:
Nutrition Care Division, Womack Army Medical Center, Fort Bragg, NC 28310-5000, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Anthropometry
Choline / blood,  pharmacology*
Cross-Over Studies
Diet Records
Double-Blind Method
Ergometry
Gas Chromatography-Mass Spectrometry
Georgia
Heart Rate / drug effects
Humans
Male
Military Personnel*
Oxygen Consumption
Physical Exertion / drug effects*
Sports
Chemical
Reg. No./Substance:
62-49-7/Choline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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