| The effects of choline supplementation on physical performance. | |
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MedLine Citation:
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PMID: 10861337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It has been reported that plasma choline levels decrease following certain types of strenuous exercise. Preliminary findings also suggest that a drop in plasma choline may limit physical performance, while choline supplementation may delay fatigue during prolonged efforts. A double-blind crossover design was used to determine the relationship between plasma choline and performance during and after 4 hr of strenuous exercise. Volunteers (N = 14) received either a placebo or treatment beverage (8.425 g choline citrate) prior to and midway through a 4-hr load carriage treadmill exercise (3% grade at 5.6 km/h 3 20 km) carrying a total load of 34.1 kg. Following the treadmill test, run time-to-exhaustion and squat tests were performed, and perceived exertion, plasma choline, glycerophosphocholine, and phosphatidylcholine were measured. Plasma choline levels increased 128% after the run-to-exhaustion with the choline supplemented beverage but remained unchanged with the placebo beverage. No significant effects were seen with choline supplementation on any outcome performance measure. Consequently, soldiers conditioned to carry heavy loads over long distances do not deplete plasma choline as a result of a prolonged exhaustive exercise under a placebo beverage, nor do they benefit from choline supplementation to delay fatigue under the same conditions. |
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Authors:
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J P Warber; J F Patton; W J Tharion; S H Zeisel; R P Mello; C P Kemnitz; H R Lieberman |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: International journal of sport nutrition and exercise metabolism Volume: 10 ISSN: 1526-484X ISO Abbreviation: Int J Sport Nutr Exerc Metab Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-08-01 Completed Date: 2000-08-01 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100939812 Medline TA: Int J Sport Nutr Exerc Metab Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 170-81 Citation Subset: IM |
Affiliation:
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Nutrition Care Division, Womack Army Medical Center, Fort Bragg, NC 28310-5000, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Anthropometry Choline / blood, pharmacology* Cross-Over Studies Diet Records Double-Blind Method Ergometry Gas Chromatography-Mass Spectrometry Georgia Heart Rate / drug effects Humans Male Military Personnel* Oxygen Consumption Physical Exertion / drug effects* Sports |
| Chemical | |
Reg. No./Substance:
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62-49-7/Choline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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