| The effects of cholesterol and β-sitosterol on the structure of saturated diacylphosphatidylcholine bilayers. | |
| | |
MedLine Citation:
|
PMID: 20978886 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The structures of DMPC and DPPC bilayers in unilamellar liposomes, in the presence of 33.3 mol% cholesterol or the plant sterol β-sitosterol, have been studied by small-angle neutron scattering. The bilayer thickness d (L) increases in a similar way for both sterols. The repeat distance in multilamellar liposomes, as determined by small-angle X-ray diffraction, is larger in the presence of β-sitosterol than in the presence of cholesterol. We observe that each sterol modifies the interlamellar water layer differently, cholesterol reducing its thickness more efficiently than β-sitosterol, and conclude that cholesterol suppresses bilayer undulations more effectively than β-sitosterol. |
| | |
Authors:
|
Jana Gallová; Daniela Uhríková; Norbert Kučerka; Slavomíra Doktorovová; Sérgio S Funari; José Teixeira; Pavol Balgavý |
Related Documents
:
|
8263786 - An alternative mechanism for the inhibition of cholesterol biosynthesis in hepg2 cells ... 17033296 - Cholesterol absorption. 19246636 - Phytosterol glycosides reduce cholesterol absorption in humans. 15465756 - Reduced and high molecular weight barley beta-glucans decrease plasma total and non-hdl... 2380266 - In vitro depolymerization dynamics of brain endogenous microtubules. 3684856 - Differential responses to dietary carbohydrates and fat of turkeys kept at various envi... |
Publication Detail:
|
Type: Journal Article Date: 2010-10-27 |
Journal Detail:
|
Title: European biophysics journal : EBJ Volume: 40 ISSN: 1432-1017 ISO Abbreviation: Eur. Biophys. J. Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8409413 Medline TA: Eur Biophys J Country: Germany |
Other Details:
|
Languages: eng Pagination: 153-63 Citation Subset: IM |
Affiliation:
|
Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University, 832 32, Bratislava, Slovakia, gallova@fpharm.uniba.sk. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lead concentrations in zooplankton, water, and particulate matter of a southwestern atlantic tempera...
Next Document: Migration and immunological reaction after the administration of ?GalCer-pulsed antigen-presenting c...