Document Detail

The effects of carbamazepine and sodium valproate on SEPs and BAEPs.
MedLine Citation:
PMID:  2444427     Owner:  NLM     Status:  MEDLINE    
SEPs and BAEPs were studied in 36 previously untreated epileptics receiving either carbamazepine (CBZ) or sodium valproate (VPA) monotherapy. CBZ prolonged central conduction times in SEPs and BAEPs. SEP latency prolongation correlated with serum CBZ levels. VPA had minimal effects on evoked potentials. The present study gives evidence of similar effects of carbamazepine and phenytoin on central neural conduction.
E Mervaala; T Keränen; P Tiihonen; P Riekkinen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Electroencephalography and clinical neurophysiology     Volume:  68     ISSN:  0013-4694     ISO Abbreviation:  Electroencephalogr Clin Neurophysiol     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-12-09     Completed Date:  1987-12-09     Revised Date:  2008-09-09    
Medline Journal Info:
Nlm Unique ID:  0375035     Medline TA:  Electroencephalogr Clin Neurophysiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  475-8     Citation Subset:  IM    
Vaajasalo Epilepsy Hospital, Kortejoki, Finland.
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MeSH Terms
Brain Stem / physiopathology*
Carbamazepine / pharmacology*,  therapeutic use
Epilepsy / drug therapy,  physiopathology
Evoked Potentials, Auditory / drug effects*
Evoked Potentials, Somatosensory / drug effects*
Middle Aged
Valproic Acid / pharmacology*,  therapeutic use
Reg. No./Substance:
298-46-4/Carbamazepine; 99-66-1/Valproic Acid

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