Document Detail


The effects of boron administration on plasma leptin and lactate levels in ovariectomized rats which had acute swimming exercise.
MedLine Citation:
PMID:  18283241     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The aim of this study was to investigate the effects of intraperitoneal (IP) boron administration on leptin and lactate levels in swimming exercise in ovariectomized rats. METHODS: Eighty adult female rats were equally allocated into 8 groups. Group 1; Control, Group 2; exercise control, Group 3; ovariectomized control, Group 4; Boron control (2 mg/kg/day), Group 5; ovariectomized plus exercise, Group 6; exercise plus IP boron, Group 7; ovariectomized and exercise group plus IP boron, Group 8; ovariectomized plus boron. RESULTS: Leptin levels in Group 1 were higher than those in Groups 2, 3 and 4 and lower than those in groups 5, 6, 7 and 8 (p<0.01). Leptin levels were higher in Group 3 than in Groups 2 and 4 and significantly lower than in all other groups (p<0.01). Lactate levels in Groups 2 and 4 were higher than those in all other groups (p<0.01). Lactate levels were significantly lower in Groups 1, 3, 5 and 8 than in all other groups (p<0.01). Lactate levels in Groups 6 and 7 were significantly lower than those in Groups 2 and 4 (p<0.01) and higher than those in groups 1, 3 and 5 (p<0.01). CONCLUSION: The present findings demonstrate that ovariectomy and acute swimming exercise in rats led to a significant decrease in leptin levels and a significant increase in lactate levels and that boron administration prevented the increased in circulating lactate concentration induced by swimming exercise.
Authors:
Zubeyde Yazici; Yalcin Kaya; Abdulkerim Kasim Baltaci; Rasim Mogulkoc; Esma Oztekin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuro endocrinology letters     Volume:  29     ISSN:  0172-780X     ISO Abbreviation:  Neuro Endocrinol. Lett.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-06     Completed Date:  2008-04-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008373     Medline TA:  Neuro Endocrinol Lett     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  173-7     Citation Subset:  IM    
Affiliation:
Department of Physical Education and Sports Sciences, Selcuk University, Konya-Turkey, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Animals
Boron / pharmacology*
Female
Lactates / blood*
Leptin / blood*
Ovariectomy*
Physical Conditioning, Animal / physiology
Rats
Rats, Sprague-Dawley
Swimming / physiology*
Trace Elements / pharmacology*
Chemical
Reg. No./Substance:
0/Lactates; 0/Leptin; 0/Trace Elements; 7440-42-8/Boron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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