Document Detail


The effects of aspirin on the CNV in healthy individuals.
MedLine Citation:
PMID:  7641247     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of aspirin on the contingent negative variation (CNV) of 16 healthy, right-handed volunteers were studied in accordance with a placebo-controlled double-blind crossover design. Early and late CNV factors were measured. Aspirin caused a statistically significant decrease of the early wave and an increase of mean amplitude of the late wave. A central action of aspirin, affecting noradrenergic and dopaminergic structures, may be responsible for the CNV changes.
Authors:
A Vein; T Voznesenskaya; A Danilov
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  15     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-09-18     Completed Date:  1995-09-18     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  129-31; discussion 78     Citation Subset:  IM    
Affiliation:
Department of Neurology, Sechenov's Moscow Medical Academy, Russia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Analysis of Variance
Aspirin / pharmacology*
Contingent Negative Variation / drug effects*
Cross-Over Studies
Double-Blind Method
Female
Humans
Male
Migraine Disorders / drug therapy,  physiopathology
Reference Values
Chemical
Reg. No./Substance:
50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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