| The effects of artificial postoperative hematoma on patency of microvascular anastomoses in rat femoral blood vessels. | |
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MedLine Citation:
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PMID: 16317928 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of hematoma formation on thrombus formation at microvascular anastomotic sites in the femoral arteries and veins of rats was investigated. No difference in anastomotic patency or thrombus formation was observed in the presence of perivascular hematoma, although compression secondary to hematoma formation was not an experimental variable. This study suggests the possibility that the velocity of blood flow (which increases with vasoconstriction) counteracts the thrombogenicity of changes in the flow volume (which decreases with vasoconstriction) by preventing the accumulation of thrombogenic materials. The authors suggest that the role of vasoconstriction in relation to thrombus formation and anastomotic patency should be explored further using topical vasoconstrictors and appropriate platelet fractions. |
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Authors:
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R Sadove; C Cline; H J Buncke |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of microsurgery Volume: 1 ISSN: 0191-3239 ISO Abbreviation: J Microsurg Publication Date: 1979 Jul-Aug |
Date Detail:
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Created Date: 2005-12-01 Completed Date: 2005-12-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8005001 Medline TA: J Microsurg Country: United States |
Other Details:
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Languages: eng Pagination: 50-5 Citation Subset: IM |
Affiliation:
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Ralph K. Davies Medical Center, San Francisco, CA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical
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adverse effects Animals Disease Models, Animal Femoral Artery / physiopathology, surgery* Femoral Vein / physiopathology, surgery* Hematoma / etiology, pathology, physiopathology* Postoperative Hemorrhage / complications*, pathology, physiopathology Rats Rats, Wistar Vascular Patency / physiology* Vascular Surgical Procedures / adverse effects*, methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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