Document Detail

The effects of ambient NO2 on lung function in primary schoolchildren.
MedLine Citation:
PMID:  8344228     Owner:  NLM     Status:  MEDLINE    
The effect of ambient NO2 on lung function was investigated in a sample of 423 schoolchildren. At each of four locations NO2 was monitored continuously. Over a 6-month period from January to June 1990 two surveys were performed and spirometry recorded each time for each child. Linear regression was used to estimate the effect of NO2 for different time intervals preceding lung function testing. A decrease of NO2 between surveys was significantly associated with a higher forced vital capacity (FVC) at the second survey. For each microgram/m3 NO2 decrease the model predicted an increase in FVC of 1.5 ml [for the 2-hr mean (P < 0.05)] and 3.1 ml [for the 12-hr mean (P < 0.01)]. We conclude that even at NO2 levels below current air-quality standards children demonstrate significant changes in lung function.
T Frischer; M Studnicka; E Beer; M Neumann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental research     Volume:  62     ISSN:  0013-9351     ISO Abbreviation:  Environ. Res.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-09-07     Completed Date:  1993-09-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147621     Medline TA:  Environ Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  179-88     Citation Subset:  IM    
University Children's Hospital, Freiburg, Germany.
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MeSH Terms
Air Pollutants / adverse effects*,  analysis
Dermatitis, Atopic / physiopathology*
Lung Diseases / physiopathology*
Models, Biological
Nitrogen Dioxide / adverse effects*,  analysis
Respiratory Function Tests
Vital Capacity*
Reg. No./Substance:
0/Air Pollutants; 10102-44-0/Nitrogen Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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