Document Detail

The effects of age and environmental temperature on the blood concentrations of glucose, free fatty acids and glycerol in new-born rabbits.
MedLine Citation:
PMID:  5767889     Owner:  NLM     Status:  MEDLINE    
1. The concentration of blood glucose, free fatty acids and serum glycerol of the doe, new-born and young rabbits have been measured in order to evaluate the effects of age, starvation and environmental temperature on the circulating concentrations of these metabolites.2. The blood glucose, free fatty acid and glycerol concentrations were lower in the new-born than in the mother rabbit.3. Starvation for 24 hr of new-born and young rabbits in a thermal neutral environment did not alter the serum free fatty acid or glycerol concentrations. The blood glucose of unfed rabbits fell during the first 24 hr of life.4. Cold exposure (15 or 25 degrees C) for 1 hr caused a rise in the concentration of blood glucose, serum free fatty acids and glycerol.5. When the metabolic response of new-born and young rabbits to cold exposure was measured, it was found that there was a direct correlation between the serum glycerol concentration and the metabolic response. The greatest rise in the serum free fatty acids occurred in the blood of rabbits with the poorest metabolic response to cold.6. It is suggested that in the steady state during cold exposure the serum glycerol concentration may indicate the rate of triglyceride hydrolysis in brown adipose tissue.
M J Hardman; D Hull
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of physiology     Volume:  201     ISSN:  0022-3751     ISO Abbreviation:  J. Physiol. (Lond.)     Publication Date:  1969 May 
Date Detail:
Created Date:  1969-06-25     Completed Date:  1969-06-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0266262     Medline TA:  J Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  685-94     Citation Subset:  IM    
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MeSH Terms
Adipose Tissue, Brown / metabolism
Age Factors
Animals, Newborn / physiology*
Basal Metabolism
Blood Glucose*
Fatty Acids, Nonesterified / blood*
Glycerol / blood*
Triglycerides / metabolism
Reg. No./Substance:
0/Blood Glucose; 0/Fatty Acids, Nonesterified; 0/Triglycerides; 56-81-5/Glycerol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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