| The effects of adenine nucleotides and guanine nucleotides on urate synthesis de novo by isolated chick liver and kidney cells. | |
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MedLine Citation:
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PMID: 173289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Isolated chick liver and kidney cells produce urate de novo from glycine, and this is partially inhibited by 1 mm-AMP and by 1 mm-GMP in liver cells but not in kidney cells. Azaserine fully inhibits this synthesis de novo, but attempts to isolate formylglycine amide ribonucleotide from azaserine-blocked cells were unsuccessful. |
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Authors:
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P Badenoch-Jones; P J Buttery |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Biochemical journal Volume: 148 ISSN: 0264-6021 ISO Abbreviation: Biochem. J. Publication Date: 1975 Jun |
Date Detail:
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Created Date: 1976-02-09 Completed Date: 1976-02-09 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2984726R Medline TA: Biochem J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 599-601 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Monophosphate
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pharmacology Animals Azaserine / pharmacology Chickens Cyclic GMP / pharmacology Glycine / analysis, metabolism Kidney / drug effects*, metabolism Liver / drug effects*, metabolism Ribosemonophosphates / analysis Uric Acid / biosynthesis* |
| Chemical | |
Reg. No./Substance:
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0/Ribosemonophosphates; 115-02-6/Azaserine; 56-40-6/Glycine; 61-19-8/Adenosine Monophosphate; 69-93-2/Uric Acid; 7665-99-8/Cyclic GMP |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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