| The effects of acute exercise and high lactate levels on 35% CO2 challenge in healthy volunteers. | |
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MedLine Citation:
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PMID: 12366475 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To test the possible antipanic effects of acute exercise in healthy volunteers exposed to an inhalation of 35% CO2 challenge. METHOD: Twenty healthy subjects in a randomized separate group design, performed exercise in a bicycle ergometer reaching >6 mm of blood lactate and a control condition of minimal activity in the same fashion with no lactate elevation. Immediately afterwards an inhalation of a vital capacity using a mixture of 35% CO2/65% O2 through a mask was given on both conditions. RESULTS: Subjects under the exercise condition reported less panic symptoms than controls after a CO2 challenge on the diagnostic statistical manual-IV (DSM-IV) Panic Symptom List but no difference on the Visual Analogue Anxiety Scale. CONCLUSION: Subjects under the exertion condition had lactate levels comparable with those of lactate infusions but an inhibitory rather than accumulative effect was seen when combined with a CO2 challenge. |
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Authors:
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G Esquivel; K Schruers; H Kuipers; E Griez |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta psychiatrica Scandinavica Volume: 106 ISSN: 0001-690X ISO Abbreviation: Acta Psychiatr Scand Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-10-07 Completed Date: 2003-03-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370364 Medline TA: Acta Psychiatr Scand Country: Denmark |
Other Details:
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Languages: eng Pagination: 394-7 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and Neuropsychology and Academic Anxiety Center, Maastricht University, Maastricht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carbon Dioxide / diagnostic use* Exercise / physiology* Exercise Test Female Humans Lactates / blood* Male Panic* Vital Capacity |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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