| The effects of acidic fluoride solutions on early enamel erosion in vivo. | |
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MedLine Citation:
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PMID: 19321990 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acidic fluoride solutions may reduce dental erosion. The aim of this study was to compare the effect of different acidic fluoride solutions on enamel dissolution using an established in vivo model. When possible 4 anterior teeth (255 teeth in a total of 67 subjects) were isolated and exposed to 0.01 M citric acid. The acid was collected in test tubes before (etch I) and 5 min after (etch II) application of test fluoride preparations. Acidic fluoride solutions (pH range 1.5-2.9), i.e. SnF(2), TiF(4) and hydrogen fluoride (HF) (all approx. 0.1 M F), HF (0.027, 0.055, 0.082 M F) and neutral NaF solution (0.1 M F) as control were applied to the labial surfaces of the teeth for 1 min (6 ml/min). Enamel dissolution was examined by chemical analysis of calcium content in the citric acid etch solutions using atom absorption spectrometry. The change in calcium concentration (DeltaCa) and the percentage of mean calcium reduction were calculated from the difference in calcium loss between etch I and etch II. Statistical analysis was carried out using the Wilcoxon signed rank test and Kruskal-Wallis tests with Dunn's multiple comparison. Results showed a mean DeltaCa of 0.671 mg/l (SD 0.625) for SnF(2), and ranged from 0.233 mg/l (SD 0.248) for the weakest HF solution to 0.373 mg/l (SD 0.310) for the strongest HF solution. This represented a 67% reduction in enamel dissolution for SnF(2) and a 40-76% reduction for the HF solutions. No reduction was observed for TiF(4) or NaF. The types of metal, pH and fluoride concentration are all important for the in vivo effect. |
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Authors:
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C Hjortsjö; G Jonski; P S Thrane; E Saxegaard; A Young |
Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2009-03-24 |
Journal Detail:
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Title: Caries research Volume: 43 ISSN: 1421-976X ISO Abbreviation: Caries Res. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-04-17 Completed Date: 2009-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0103374 Medline TA: Caries Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 126-31 Citation Subset: D; IM |
Copyright Information:
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2009 S. Karger AG, Basel. |
Affiliation:
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Department of Prosthodontics, Faculty of Dentistry, University of Oslo, Oslo, Norway. carl.hjortsjo@odont.uio.no |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Calcium / analysis Cariostatic Agents / therapeutic use* Citric Acid / pharmacology Dental Enamel / drug effects* Dental Enamel Solubility / drug effects Dose-Response Relationship, Drug Fluorides / therapeutic use* Humans Hydrofluoric Acid / administration & dosage, therapeutic use Hydrogen-Ion Concentration Middle Aged Protective Agents / therapeutic use Single-Blind Method Sodium Fluoride / therapeutic use Spectrophotometry, Atomic Time Factors Tin Fluorides / therapeutic use Titanium / therapeutic use Tooth Erosion / prevention & control* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Cariostatic Agents; 0/Fluorides; 0/Protective Agents; 0/Tin Fluorides; 7440-32-6/Titanium; 7440-70-2/Calcium; 7664-39-3/Hydrofluoric Acid; 7681-49-4/Sodium Fluoride; 77-92-9/Citric Acid; 7783-63-3/titanium tetrafluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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