Document Detail


The effects of acetylsalicylic acid on the pituitary prolactin of the lizard, Uromastix hardwickii.
MedLine Citation:
PMID:  16380343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study deals with the intravenous administration of 7 mg acetylsalicylic acid (ASA) solution to Uromastix hardwickii for 4 days. It enhances the activity of anterior pituitary lactotrophs, when 0.1 ml of pituitary homogenate of ASA treated was injected hypodermically to crop-sac showed a greater diametric response and increased activity with milk like secretion than that of the injections of 0.1 ml homogenate of control pituitary. The present study indicated that ASA induces hyperprolactinemia.
Authors:
Mahmood Ahmad; Ruqaiya Hasan; Mansoor Ahmad; Anila Qureshi; Shama Masroor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pakistan journal of pharmaceutical sciences     Volume:  18     ISSN:  1011-601X     ISO Abbreviation:  Pak J Pharm Sci     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-12-28     Completed Date:  2006-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426356     Medline TA:  Pak J Pharm Sci     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  42-5     Citation Subset:  IM    
Affiliation:
Department of Physiology, University of Karachi, Karachi-75270, Pakistan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aspirin / pharmacology*
Cyclooxygenase Inhibitors / pharmacology
Lizards
Pituitary Gland, Anterior / drug effects*,  secretion
Prolactin / secretion*
Prostaglandins / physiology
Chemical
Reg. No./Substance:
0/Cyclooxygenase Inhibitors; 0/Prostaglandins; 50-78-2/Aspirin; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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