| The effects of abdominal irradiation for seminoma of the testis on gastrointestinal function. | |
| | |
MedLine Citation:
|
PMID: 7787155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To evaluate the long-term effects of abdominal irradiation for the treatment of seminoma of the testis on gastrointestinal function, 15 randomly selected patients who had been treated for stage I seminoma of the testis 2-10 years previously had the following parameters of gastrointestinal function evaluated: gastrointestinal symptoms; absorption of bile acid; vitamin B12; lactose and fat; gastric emptying; small intestinal and total gut transit; and intestinal permeability. Results were compared to those obtained in 18 normal volunteers. There was an increased prevalence of gastrointestinal symptoms (P < 0.01) in the patients and stool frequency was above the control range in two of them. Gastric emptying was faster (P < 0.01) in the patients. There were no significant differences in vitamin B12, bile acid, lactose or fat absorption, small intestinal transit or whole gut transit between the two groups, although faecal fat excretion was greater than the control range in three of the patients. At least one parameter of gastrointestinal function was abnormal in 11 of the 15 patients. Patients with right-sided seminoma had a greater bowel frequency when compared to those with left-sided seminoma (P < 0.05). We conclude that mild abnormalities in gastrointestinal function occur frequently when abdominal irradiation is used to treat stage I seminoma. |
| | |
Authors:
|
E Yeoh; M Horowitz; A Russo; T Muecke; T Robb; B Chatterton |
Related Documents
:
|
2345785 - D-lactic acidosis in short bowel syndrome--an examination of possible mechanisms. 8427005 - Chilaiditi's syndrome as a surgical and nonsurgical problem. 15547835 - Experience of long-term synbiotic therapy in seven short bowel patients with refractory... 18026735 - Uncommon causes of postoperative chronic diarrhoea mimicking enterocolitis in hirschspr... 6462735 - Sexual dysfunction after spinal cord or cauda equina lesions. 17804675 - Chronic peritoneal dialysis in the united states: declining utilization despite improvi... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of gastroenterology and hepatology Volume: 10 ISSN: 0815-9319 ISO Abbreviation: J. Gastroenterol. Hepatol. Publication Date: 1995 Mar-Apr |
Date Detail:
|
Created Date: 1995-07-25 Completed Date: 1995-07-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: AUSTRALIA |
Other Details:
|
Languages: eng Pagination: 125-30 Citation Subset: IM |
Affiliation:
|
Department of Radiation Oncology, Royal Adelaide Hospital, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abdomen
/
radiation effects Adult Aged Digestive System / physiopathology, radiation effects* Follow-Up Studies Gastrointestinal Diseases / etiology Gastrointestinal Transit / radiation effects Humans Intestinal Absorption / radiation effects Male Middle Aged Permeability / radiation effects Radiotherapy / adverse effects Seminoma / radiotherapy* Testicular Neoplasms / radiotherapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ras oncogene and p53 gene hotspot mutations in colorectal cancers.
Next Document: Familial juvenile polyposis with adenomatous-carcinomatous change.