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The effects of 8 weeks of endurance running on hepcidin concentrations, inflammatory parameters, and iron status in female runners.
MedLine Citation:
PMID:  22248501     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Exercise-associated iron deficiency is a common disorder in endurance athletes. The authors investigated the effects of long-term endurance exercise on hepcidin concentrations, inflammatory parameters, and iron status in moderately trained female long-distance runners. Eighteen runners were assigned to either an interval- or a continuous-training exercise group. The physical training consisted of two 3-week progressive overload periods, each followed by a week's recovery, and concluded with a 10- or 21-km competitive run. Samples were taken 6 times during the 8-wk training program, first at baseline (BPre), then after the first and second 3-wk training loads (TPost1, TPost2), after each recovery week (Recovery1 and Recovery2), and poststudy (BPost). Soluble transferrin receptor (sTfR) concentrations were increased in Recovery2 and BPost compared with BPre (p = .02), hemoglobin decreased in TPost1 and TPost2 (p < .001), and red blood cells decreased in TPost2 (p = .01). Hepcidin decreased with time in TPost1 and in BPost compared with BPre (p < .001) and increased in TPost2 compared with TPost1 (p < .001). No differences over time were found for high-sensitivity C-reactive protein. The main findings of the current study indicate that serum hepcidin and sTfR were affected after 8 weeks of endurance running in women. No positive relation was found with inflammation.
Authors:
Irena Auersperger; Bojan Knap; Ales Jerin; Rok Blagus; Mitja Lainscak; Milan Skitek; Branko Skof
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  22     ISSN:  1543-2742     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  55-63     Citation Subset:  IM    
Affiliation:
Faculty of Sport, and Blagus, the Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
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