| An effectiveness trial of multiple micronutrient supplementation during pregnancy in Vietnam: impact on birthweight and on stunting in children at around 2 years of age. | |
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MedLine Citation:
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PMID: 20120792 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Multiple micronutrient deficiencies during pregnancy in Vietnam may contribute to poor fetal growth and stunting, which are major determinants of the health and development offuture generations. OBJECTIVE: We assessed the effects of prenatal multiple micronutrient supplementation on maternal weight gain during pregnancy, infant birthweight, and height of the child at around 2 years of age. METHODS: We conducted a nonrandomized, non-blinded, side-by-side effectiveness trial in a normal program setting in three districts in the Red River Delta in the north of Vietnam. Women in one district received the standard iron-folic acid supplement during prenatal care; women in the second district received the multiple micronutrient supplement; in the third district, gender training was provided in addition to the multiple micronutrient supplement. Cluster surveys were carried out in the three districts at the end of the trial to verify low birthweight (LBW) and at around 2 years after the trial to measure children's height and weight, as well as to collect demographic data on the mothers. RESULTS: Mean birthweight was higher in the districts receiving multiple micronutrient supplements than in the district receiving iron-folic acid tablets. The mean birthweight was 166 g higher in the district receiving multiple micronutrients and 105 g higher in the district receiving multiple micronutrients with gender training than in the district receiving iron-folic acid (p < .05). The prevalence of LBW children (< 2500 g) was lower in the district receiving multiple micronutrients (4.0%) and the district receiving multiple micronutrients plus gender training (5.8%) than in the district receiving iron-folic acid (10.6%) (p < .05). Children at around 2 years of age were taller in the district receiving multiple micronutrients (82.66 cm) and the district receiving multiple micronutrients plus gender training (83.61 cm) than in the district receiving iron-folic acid (81.64 cm), and the stunting rates were about 10% lower than in the district receiving iron-folic acid. CONCLUSIONS: Multiple micronutrient supplementation during pregnancy could be an important intervention to help reduce stunting rates in Vietnam. |
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Authors:
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Nguyen Do Huy; Thi Le Hop; Roger Shrimpton; Cao Viet Hoa |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Food and nutrition bulletin Volume: 30 ISSN: 0379-5721 ISO Abbreviation: Food Nutr Bull Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-03-11 Revised Date: 2010-05-18 |
Medline Journal Info:
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Nlm Unique ID: 7906418 Medline TA: Food Nutr Bull Country: Japan |
Other Details:
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Languages: eng Pagination: S506-16 Citation Subset: IM |
Affiliation:
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National Institute of Nutrition, Hanoi, Vietnam. nguyendo-huy@dinhduong.org.vn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anemia / drug therapy, epidemiology, prevention & control Birth Weight Child Development* Child, Preschool Dietary Supplements* Female Fetal Development* Fetal Growth Retardation / epidemiology, prevention & control Humans Infant, Newborn Male Maternal Nutritional Physiological Phenomena* Micronutrients / administration & dosage*, deficiency Pregnancy Pregnancy Complications / drug therapy, epidemiology, prevention & control Pregnancy Outcome Premature Birth / epidemiology, prevention & control Prevalence Rural Population Vietnam / epidemiology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Micronutrients |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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