Document Detail


The effect of vitamin E treatment during preovulatory period on reproductive performance of goats following estrous synchronization using intravaginal sponges.
MedLine Citation:
PMID:  18950971     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objectives of this study were to investigate whether the use of intravaginal sponge for estrous synchronization of goats causes oxidative stress, and to examine the effect of administering vitamin E during preovulatory period on reproductive performance of estrous synchronized goats. Estrus was synchronized in 36 non-lactating adult does using intravaginal sponges containing 30 mg of fluorogestane acetate (FGA) for 14 days. All females received 500 IU of eCG at the sponge withdrawal. The goats were allocated at random to two groups balanced for breed, age and body weight. Treatment group (n=18) received 200mg of vitamin E i.m. at the time of sponge removal and again at the time of second artificial insemination. The other 18 goats (control) were administered 1 ml of physiological saline instead of vitamin E on each of these two occasions. All does in estrus was intracervically inseminated at 12 and 24h after the onset of estrus. Blood samples were collected every 72h during the experimental period for evaluation of malondialdehyde (MDA) and vitamin E concentrations. Serum MDA level increased and vitamin E concentration decreased during the period of vaginal sponge application. Following the sponge removal, MDA level declined rapidly to below basal level in the treatment group but remained high in the control group. Conversely, vitamin E concentration increased in the treatment group after the sponge withdrawal and remained at a low level in the control group. No statistically significant differences (P>0.05) were observed between groups in terms of estrous response, conception rate, gestation length or kidding rate. However, the number of multiple births (70.0% versus 50.0%) and prolificacy rate (2.40+/-0.37 versus 1.63+/-0.26 kids per kidding) were significantly higher (P<0.05) for the treatment group than those of the control group. The results indicate that the use of intravaginal sponges for estrous synchronization of goats causes an increase in level of oxidative stress. However, the vitamin E treatment during preovulatory period can prevent the overproduction of reactive oxygen species (ROS), and it may improve the multiple birth rates and the number of kids born in estrous synchronized goats.
Authors:
Mustafa Sönmez; Tanzer Bozkurt; Gaffari Türk; Seyfettin Gür; Meltem Kizil; Abdurrauf Yüce
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-09-12
Journal Detail:
Title:  Animal reproduction science     Volume:  114     ISSN:  1873-2232     ISO Abbreviation:  Anim. Reprod. Sci.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-06-02     Completed Date:  2009-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807205     Medline TA:  Anim Reprod Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  183-92     Citation Subset:  IM    
Affiliation:
Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine, Firat University, 23119 Elaziğ, Turkey. msonmezvet@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Chorionic Gonadotropin / pharmacology
Estrus Synchronization*
Female
Flurogestone Acetate / pharmacology
Goats
Insemination, Artificial / veterinary
Malondialdehyde / blood
Ovulation / drug effects*
Pregnancy
Thiobarbituric Acid Reactive Substances
Vitamin E / administration & dosage*,  pharmacology*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Thiobarbituric Acid Reactive Substances; 1406-18-4/Vitamin E; 2529-45-5/Flurogestone Acetate; 542-78-9/Malondialdehyde

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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