| The effect of vessel material properties and pulsatile wall motion on the fixation of a proximal stent of an endovascular graft. | |
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MedLine Citation:
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PMID: 20947409 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Migration is a serious failure mechanism associated with endovascular abdominal aortic aneurysm (AAA) repair (EVAR). The effect of vessel material properties and pulsatile wall motion on stent fixation has not been previously investigated. A proximal stent from a commercially available stent graft was implanted into the proximal neck of silicone rubber abdominal aortic aneurysm models of varying proximal neck stiffness (β=25.39 and 20.44). The stent was then dislodged by placing distal force on the stent struts. The peak force to completely dislodge the stent was measured using a loadcell. Dislodgment was performed at ambient pressure with no flow (NF) and during pulsatile flow (PF) at pressures of 120/80 mmHg and 140/100 mmHg to determine if pulsatile wall motions affected the dislodgement force. An imaging analysis was performed at ambient pressure and at pressures of 120 mmHg and 140 mmHg to investigate diameter changes on the model due to the radial force of the stent and internal pressurisation. Stent displacement forces were ~50% higher in the stiffer model (7.16-8.4 N) than in the more compliant model (3.67-4.21 N). The mean displacement force was significantly reduced by 10.95-12.83% from the case of NF to the case of PF at 120/80 mmHg. A further increase in pressure to 140/120 mmHg had no significant effect on the displacement force. The imaging analysis showed that the diameter in the region of the stent was 0.37 mm greater in the less stiff model at all the pressures which could reduce the fixation of the stent. The results suggest that the fixation of passively fixated aortic stents could be comprised in more compliant walls and that pulsatile motions of the wall can reduce the maximum stent fixation. |
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Authors:
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T J Corbett; D S Molony; A Callanan; T M McGloughlin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-10-14 |
Journal Detail:
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Title: Medical engineering & physics Volume: 33 ISSN: 1873-4030 ISO Abbreviation: Med Eng Phys Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9422753 Medline TA: Med Eng Phys Country: England |
Other Details:
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Languages: eng Pagination: 106-11 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 IPEM. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for Applied Biomedical Engineering Research (CABER), MSSi, Department of Mechanical and Aeronautical Engineering, University of Limerick, Limerick, Ireland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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