Document Detail


The effect of vasoactive agents on the contractions of the initial lymphatics of the bat's wing.
MedLine Citation:
PMID:  2882795     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of vasoactive agents on the spontaneous contractions of the initial lymphatics of the bat's wing was investigated. Initial lymphatic contractile frequency and pulsatile pressure were measured with the servo-null micropressure system. Norepinephrine, phenylepinephrine, isoproterenol, acetylcholine, histamine, serotonin, bradykinin, prostaglandin F2a, prostaglandin E2, indomethacin and ibuprofen were delivered to the immediate vicinity of the initial lymphatic by microinjection or iontophoresis. Only bradykinin produced changes in initial lymphatic contractions which were significantly different from control. The response to bradykinin was characterized by an increase in the frequency, strength or duration of the contraction.
Authors:
J L Unthank; R D Hogan
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Blood vessels     Volume:  24     ISSN:  0303-6847     ISO Abbreviation:  Blood Vessels     Publication Date:  1987  
Date Detail:
Created Date:  1987-06-17     Completed Date:  1987-06-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0427130     Medline TA:  Blood Vessels     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  31-44     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bradykinin / pharmacology
Chiroptera / physiology*
Dinoprost
Histamine / pharmacology
Ibuprofen / pharmacology
Indomethacin / pharmacology
Lymphatic System / drug effects*
Neurotransmitter Agents / pharmacology*
Prostaglandins F / pharmacology
Vasoconstrictor Agents / pharmacology*
Vasodilator Agents / pharmacology*
Wing / drug effects
Grant Support
ID/Acronym/Agency:
HL 28733/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Neurotransmitter Agents; 0/Prostaglandins F; 0/Vasoconstrictor Agents; 0/Vasodilator Agents; 15687-27-1/Ibuprofen; 51-45-6/Histamine; 53-86-1/Indomethacin; 551-11-1/Dinoprost; 58-82-2/Bradykinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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