| The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis. | |
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MedLine Citation:
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PMID: 15759023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is to compare the effect of antihypertensive drug therapy and balloon angioplasty on quality of life in patients with hypertension and renal artery stenosis. We compared the quality of life in 56 patients randomised to balloon angioplasty to that in 50 patients randomised to antihypertensive drug therapy after 3 and 12 months of follow-up. Quality of life was measured using a questionnaire on physical symptoms associated with hypertension and antihypertensive drugs, and two generic health questionnaires (MOS Survey and EuroQol instrument). After follow-up, the patients who underwent angioplasty used less antihypertensive drugs than the patients who were treated with antihypertensive drugs only (mean+/-s.d., 1.9+/-0.9 vs 2.5+/-1.0 drugs after 3 months, P=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life. |
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Authors:
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P Krijnen; B C van Jaarsveld; M G M Hunink; J D F Habbema |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of human hypertension Volume: 19 ISSN: 0950-9240 ISO Abbreviation: J Hum Hypertens Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-05-19 Completed Date: 2005-08-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: England |
Other Details:
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Languages: eng Pagination: 467-70 Citation Subset: IM |
Affiliation:
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Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. p.krijnen@ikw.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Balloon* Antihypertensive Agents / therapeutic use* Female Follow-Up Studies Humans Hypertension / drug therapy*, etiology, physiopathology* Male Middle Aged Quality of Life* Questionnaires Renal Artery Obstruction / complications, physiopathology*, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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