Document Detail

The effect of a topical insecticide containing permethrin on the number of Culicoides midges caught near horses with and without insect bite hypersensitivity in the Netherlands.
MedLine Citation:
PMID:  18975624     Owner:  NLM     Status:  MEDLINE    
Insect bite hypersensitivity (IBH) in horses is most likely caused by Culicoides species, although other insects may also play a role. Until now no effective cure has been found for this condition, although numerous therapeutic and preventive measures have been used to control insect hypersensitivity. One such method is to apply a topical insecticide to horses. In this study, the effect of a topical insecticide containing permethrin (3.6%) was examined in seven pairs of horses. The horses were placed inside a tent trap to collect Culicoides spp. and other insects attracted to the horses on two subsequent evenings. On the first evening, both horses were untreated. After the end of this session, one horse of each pair was treated with the pour-on insecticide; treated horses were kept separate from untreated horses. The next evening the pairs of horses were again placed inside the tent trap and insects were collected. Similar percentages of Culicoides were trapped as in earlier studies (C. obsoletus 95.34% and C. pulicaris 4.54%), with healthy horses attracting more Culicoides than horses affected by IBH. The number of Culicoides, the percentage of blood-fed Culicoides obsoletus, and the total number of insects attracted to horses 24 hours after treatment with permethrin were reduced but the reduction was not statistically significant. No negative side effects of permethrin administration were observed.
I J de Raat; R van den Boom; M van Poppel; M M Sloet van Oldruitenborgh-Oosterbaan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tijdschrift voor diergeneeskunde     Volume:  133     ISSN:  0040-7453     ISO Abbreviation:  Tijdschr Diergeneeskd     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-11-03     Completed Date:  2008-12-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0031550     Medline TA:  Tijdschr Diergeneeskd     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  838-42     Citation Subset:  IM    
Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1I4, 3584 CM, the Netherlands.
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MeSH Terms
Administration, Topical
Ceratopogonidae* / drug effects,  immunology,  physiology
Horse Diseases / immunology*,  prevention & control
Hypersensitivity / immunology,  veterinary*
Insect Bites and Stings / immunology,  prevention & control,  veterinary*
Insecticides / adverse effects,  pharmacology*
Permethrin / adverse effects,  pharmacology*
Treatment Outcome
Reg. No./Substance:
0/Insecticides; 52645-53-1/Permethrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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