Document Detail


The effect of a thiamin derivative on exercise performance.
MedLine Citation:
PMID:  9202948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the effect of a thiamin derivative, thiamin tetrahydrofurfuryl disulfide (TTFD), on oxygen uptake (VO2), lactate accumulation and cycling performance during exercise to exhaustion. Using a randomized, double-blind, cross-over design with a 10-day washout between trials, 14 subjects ingested either 1 g.day-1 of TTFD or a placebo (PL) for 4 days. On day 3, subjects performed a progressive exercise-test to exhaustion on a cycle ergometer for the determination of VO2submax, VO2peak, lactate concentration ([La-]), lactate threshold (ThLa) and heart rate (fc). On day 4, subjects performed a maximal 2000-m time trial on a cycle ergometer. A one-way analysis of variance (ANOVA) with repeated measures was used to determine significant differences between trials. There were no significant differences detected between trials for serial measures of VO2submax, [La-] or fc. Likewise, VO2peak [PL 4.06 (0.19) TTFD 4.12 (0.19) l.min-1, P = 0.83], ThLa [PL 2.47 (0.17), TTFD 2.43 (0.16) l.min-1, P = 0.86] and 2000-m performance time [PL 204.5 (5.5), TTFD 200.9 (4.3).s, P = 0.61] were not significantly different between trials. The results of this study suggest that thiamin derivative supplementation does not influence high-intensity exercise performance.
Authors:
M J Webster; T P Scheett; M R Doyle; M Branz
Related Documents :
18952058 - Role of gpr81 in lactate-mediated reduction of adipose lipolysis.
22606868 - Common mental disorders among civil aviation pilots.
12623628 - Wheelchair racing efficiency.
12362418 - Microdialysis and electromyography of experimental muscle fatigue in healthy volunteers...
17616468 - Otolith crystals (in carapidae): growth and habit.
8376908 - Atrial natriuretic peptide response to postural changes and upright exercise in patient...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of applied physiology and occupational physiology     Volume:  75     ISSN:  0301-5548     ISO Abbreviation:  Eur J Appl Physiol Occup Physiol     Publication Date:  1997  
Date Detail:
Created Date:  1997-08-05     Completed Date:  1997-08-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410266     Medline TA:  Eur J Appl Physiol Occup Physiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  520-4     Citation Subset:  IM    
Affiliation:
Department of Physical Education, Western Illinois University, Macomb 61455, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Cross-Over Studies
Double-Blind Method
Exercise / physiology*
Female
Fursultiamin / pharmacology*
Heart Rate / drug effects
Humans
Lactic Acid / metabolism
Male
Oxygen Consumption / drug effects
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid; 804-30-8/Fursultiamin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The influence of maximal aerobic power on recovery of skeletal muscle following anaerobic exercise.
Next Document:  Effects of different carbohydrate-electrolyte beverages on the appearance of ingested deuterium in b...