| The effect of a thiamin derivative on exercise performance. | |
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MedLine Citation:
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PMID: 9202948 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to investigate the effect of a thiamin derivative, thiamin tetrahydrofurfuryl disulfide (TTFD), on oxygen uptake (VO2), lactate accumulation and cycling performance during exercise to exhaustion. Using a randomized, double-blind, cross-over design with a 10-day washout between trials, 14 subjects ingested either 1 g.day-1 of TTFD or a placebo (PL) for 4 days. On day 3, subjects performed a progressive exercise-test to exhaustion on a cycle ergometer for the determination of VO2submax, VO2peak, lactate concentration ([La-]), lactate threshold (ThLa) and heart rate (fc). On day 4, subjects performed a maximal 2000-m time trial on a cycle ergometer. A one-way analysis of variance (ANOVA) with repeated measures was used to determine significant differences between trials. There were no significant differences detected between trials for serial measures of VO2submax, [La-] or fc. Likewise, VO2peak [PL 4.06 (0.19) TTFD 4.12 (0.19) l.min-1, P = 0.83], ThLa [PL 2.47 (0.17), TTFD 2.43 (0.16) l.min-1, P = 0.86] and 2000-m performance time [PL 204.5 (5.5), TTFD 200.9 (4.3).s, P = 0.61] were not significantly different between trials. The results of this study suggest that thiamin derivative supplementation does not influence high-intensity exercise performance. |
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Authors:
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M J Webster; T P Scheett; M R Doyle; M Branz |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of applied physiology and occupational physiology Volume: 75 ISSN: 0301-5548 ISO Abbreviation: Eur J Appl Physiol Occup Physiol Publication Date: 1997 |
Date Detail:
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Created Date: 1997-08-05 Completed Date: 1997-08-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0410266 Medline TA: Eur J Appl Physiol Occup Physiol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 520-4 Citation Subset: IM |
Affiliation:
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Department of Physical Education, Western Illinois University, Macomb 61455, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cross-Over Studies Double-Blind Method Exercise / physiology* Female Fursultiamin / pharmacology* Heart Rate / drug effects Humans Lactic Acid / metabolism Male Oxygen Consumption / drug effects |
| Chemical | |
Reg. No./Substance:
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50-21-5/Lactic Acid; 804-30-8/Fursultiamin |
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