| The effect of temperature on the alpha-adrenoceptor antagonist potency of indoramin and labetalol in the rat perfused mesenteric vascular bed. | |
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MedLine Citation:
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PMID: 6149291 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of reduction in temperature of perfusion from 37 to 27 degrees C and 20 degrees C on the ability of the adrenoceptor antagonists indoramin and labetalol to block pressor responses to noradrenaline in the perfused mesenteric vascular bed of the rat was examined. The results suggest that in rat mesenteric bed, antagonist potency of both agents is increased at low temperatures. |
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Authors:
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R P McAdams |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pharmacy and pharmacology Volume: 36 ISSN: 0022-3573 ISO Abbreviation: J. Pharm. Pharmacol. Publication Date: 1984 Sep |
Date Detail:
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Created Date: 1984-12-20 Completed Date: 1984-12-20 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0376363 Medline TA: J Pharm Pharmacol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 628-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Antagonists
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pharmacology* Animals Ethanolamines / pharmacology* Indoles / pharmacology* Indoramin / pharmacology* Labetalol / pharmacology* Male Perfusion Rats Rats, Inbred Strains Splanchnic Circulation / drug effects* Temperature |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Antagonists; 0/Ethanolamines; 0/Indoles; 26844-12-2/Indoramin; 36894-69-6/Labetalol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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