| The effect of sub-Tenon lidocaine injection on emergence agitation after general anaesthesia in paediatric strabismus surgery. | |
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MedLine Citation:
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PMID: 21206277 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVE: Sevoflurane is widely used for paediatric anaesthesia. However, many cases of emergence agitation after sevoflurane anaesthesia have been reported and pain was suggested as a major contributing factor. The purpose of this study was to evaluate the effect of sub-Tenon lidocaine injection on emergence agitation in children receiving sevoflurane or propofol-remifentanil anaesthesia. METHODS: We enrolled 260 children, aged 4-10 years, who were scheduled for strabismus surgery, and randomized them to one of four groups: group SS, SL, BS, and BL. Anaesthesia was maintained with sevoflurane (SS, SL) or propofol-remifentanil infusion (BS, BL). At the end of surgery, the surgeon injected into the sub-Tenon space 1 ml of isotonic saline (SS, BS) or 2% lidocaine (SL, BL). Emergence behaviour was assessed in the post-anaesthesia care unit using a 5-point scoring scale (score 1, asleep; 2, awake and calm; 3, irritable or consolable crying; 4, inconsolable crying; and 5, severe restlessness). We defined a score of 4 or 5 as emergence agitation. The incidence of emergence agitation was analysed using χ² and Fisher's exact test. RESULTS: The incidence of emergence agitation in group SL and BL was significantly lower compared to group SS and BS, respectively (P = 0.011, 0.019). The lidocaine-injected group showed significantly lower occurrence of emergence agitation (10.4%) than isotonic saline-injected group (27.2%; P = 0.001). Emergence agitation was significantly higher following sevoflurane (25.0%) than balanced anaesthesia (13.1%; P = 0.023). CONCLUSION: The frequency of emergence agitation is significantly reduced by sub-Tenon lidocaine injection regardless of the modality of anaesthesia used. |
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Authors:
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Il-Sook Seo; Chae-Rim Seong; Gul Jung; Sang-Jin Park; Sae Yeon Kim; Myung Mi Kim |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of anaesthesiology Volume: 28 ISSN: 1365-2346 ISO Abbreviation: Eur J Anaesthesiol Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-13 Completed Date: 2011-07-29 Revised Date: 2012-01-09 |
Medline Journal Info:
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Nlm Unique ID: 8411711 Medline TA: Eur J Anaesthesiol Country: England |
Other Details:
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Languages: eng Pagination: 334-9 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology and Pain Medicine, Yeungnam University Hospital, Daegu, Republic of Korea. isseo@med.yu.ac.kr |
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| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia Recovery Period Anesthesia, General / adverse effects*, methods Anesthetics, Combined / administration & dosage, adverse effects, therapeutic use Anesthetics, Inhalation / administration & dosage, adverse effects, therapeutic use Anesthetics, Intravenous / administration & dosage, adverse effects, therapeutic use Anesthetics, Local / administration & dosage, therapeutic use* Child Child, Preschool Female Follow-Up Studies Humans Incidence Lidocaine / administration & dosage, therapeutic use* Male Methyl Ethers / adverse effects, therapeutic use Ophthalmologic Surgical Procedures Pain, Postoperative / complications, prevention & control Piperidines / administration & dosage, adverse effects, therapeutic use Propofol / administration & dosage, adverse effects, therapeutic use Psychomotor Agitation / epidemiology, etiology, prevention & control* Strabismus / surgery |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Combined; 0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 0/Anesthetics, Local; 0/Methyl Ethers; 0/Piperidines; 132875-61-7/remifentanil; 137-58-6/Lidocaine; 2078-54-8/Propofol; 28523-86-6/sevoflurane |
| Comments/Corrections | |
Comment In:
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Eur J Anaesthesiol. 2012 Jan;29(1):52-3; author reply 53
[PMID:
21540745
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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