Document Detail


The effect of spironolactone on the rat uterus.
MedLine Citation:
PMID:  7745376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our experimental study showed that in a dose related manner SP has successful inhibitory effect on the rat uterine horn, and also on the smooth muscle organs; ileum and trachea. We guess that SP can be used in well regulated dosed with least side effects to arrest preterm labor on human being in the future. Up to date there is no manuscript about contraction inhibitory effect of SP on the uterus. We hope this study will be of scientific help.
Authors:
B Coksevim; M Tayyar
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  77     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-06-14     Completed Date:  1995-06-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  539-43     Citation Subset:  IM    
Affiliation:
Department of Physiology, Faculty of Medicine, University of Erciyes, Kayseri, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Animals
Diethylstilbestrol / pharmacology
Dose-Response Relationship, Drug
Female
Ileum / drug effects
Isoxsuprine / administration & dosage,  pharmacology
Muscle Contraction / drug effects
Rats
Rats, Inbred Strains
Ritodrine / administration & dosage,  pharmacology
Spironolactone / administration & dosage,  pharmacology*
Trachea / drug effects
Uterine Contraction / drug effects*
Chemical
Reg. No./Substance:
26652-09-5/Ritodrine; 395-28-8/Isoxsuprine; 52-01-7/Spironolactone; 56-53-1/Diethylstilbestrol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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