Document Detail


The effect of smoking cessation on quality of life after lung cancer surgery.
MedLine Citation:
PMID:  21498082     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective: This study aimed to evaluate the effect of smoking status on quality of life (QoL) after non-small-cell lung cancer surgery with the European Organisation for Research and Treatment of Cancer (EORTC) QoL Questionnaire-C30 and LC13. Methods: QoL was prospectively recorded in 70 consecutive patients undergoing lobectomy or pneumonectomy. Questionnaires were administered preoperatively and 1, 3, 6 and 12 months postoperatively (MPO). Results: Of all patients analysed, nine (13%) were non-smokers, 20 (29%) former smokers, six (8%) recent quitters and 35 (50%) current smokers. All four groups had comparable patients' characteristics and preoperative QoL scores, with exception of non-smokers who had significantly lower physical functioning, role functioning, cognitive functioning and a higher thoracic pain burden. In non-smokers, all QoL scores returned to baseline 3 months after surgery. Former smokers complained of a significant 3-month decrease in physical functioning (3 MPO, p=0.01) and a 12-month decrease in role functioning (12 MPO, p=0.01). Former smokers complained of a significant increase in dyspnoea (6 MPO, p=0.001) during the first 6 months after surgery. Recent quitters had a longer impairment in physical functioning (6 MPO, p=0.01) and a 3-month burden of dyspnoea (3 MPO, p=0.02). In current smokers, no return to baseline in physical (12 MPO, p=0.01), role (12 MPO, p=0.01) and social functioning (12 MPO, p=0.02) and a persistent increase in dyspnoea (12 MPO, p=0.04) were reported. Current smokers also complained of increased thoracic pain (12 MPO, p=0.02). Except non-smokers, all patients complained of fatigue the first 3 months after surgery. Conclusions: Smoking cessation is beneficial at any time point to lung cancer surgery and current smoking at the time of surgery is associated with a poor postoperative QoL.
Authors:
Bram Balduyck; Peyman Sardari Nia; Anouschka Cogen; Yanina Dockx; Patrick Lauwers; Jeroen Hendriks; Paul Van Schil
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-16
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  -     ISSN:  1873-734X     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
Affiliation:
Antwerp University Hospital, Edegem, Belgium.
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