Document Detail

The effect of single morning and evening rinses of chlorhexidine on the development of tooth staining and plaque accumulation. A blind cross-over trial.
MedLine Citation:
PMID:  6951838     Owner:  NLM     Status:  MEDLINE    
A dietary aetiology for tooth staining associated with the use of chlorhexidine has been postulated. The time related activity of chlorhexidine would therefore suggest that evening rinsing would result in less staining than morning rinsing. This study measured tooth and tongue staining and plaque accumulation in a group of 18 volunteers, rinsing once at night or once in the morning with chlorhexidine in a blind cross-over design. Beverage intake during two 10-day periods was prescribed. Significantly more tooth staining, but not tongue staining, was seen with morning rinsing. Plaque accumulation showed a trend to more plaque with morning rinsing, which was not significant. The findings would be consistent with a dietary aetiology for tooth staining. However, these results emphasise the considerable duration of activity of chlorhexidine on surfaces in the oral cavity and the theory of progressive desorption of chlorhexidine from the tooth surface is questioned.
M Addy; J Moran; R M Davies; A Beak; A Lewis
Related Documents :
1716818 - Elisa analysis of soybean trypsin inhibitors in processed foods.
23578298 - Is there an association between microbial exposure and food allergy? a systematic review.
9448788 - The plaque acidogenic response to carbohydrates of children from three ethnic groups in...
8902238 - Effect of calcination on sintering of hydroxyapatite.
24709368 - A multiplex pcr/ldr assay for simultaneous detection and identification of the niaid ca...
9152568 - The effect of food intake on the pharmacokinetics of sustained-release morphine sulfate...
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of clinical periodontology     Volume:  9     ISSN:  0303-6979     ISO Abbreviation:  J. Clin. Periodontol.     Publication Date:  1982 Mar 
Date Detail:
Created Date:  1982-07-19     Completed Date:  1982-07-19     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0425123     Medline TA:  J Clin Periodontol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  134-40     Citation Subset:  D; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chlorhexidine / administration & dosage*,  adverse effects
Dental Plaque / prevention & control*
Time Factors
Tooth Discoloration / chemically induced*
Reg. No./Substance:
0/Mouthwashes; 55-56-1/Chlorhexidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Induction of estrogen sulfotransferase in the human endometrium by progesterone in organ culture.
Next Document:  Regeneration of infrabony periodontal defects in humans after implantation of allogenic demineralize...