| The effect of simultaneous use of respiratory triggering in diffusion-weighted imaging of the liver. | |
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MedLine Citation:
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PMID: 17139138 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the effect of simultaneous use of respiratory triggering in hepatic diffusion-weighted imaging (DWI), we compared DWI with respiratory triggering (RT-DWI) and DWI under free breathing (FB-DWI) in terms of relative contrast between hepatic tumor and surrounding liver parenchyma, apparent diffusion coefficient (ADC) measurement, and frequency of respiratory misregistration. MATERIALS AND METHODS: Thirty patients (21 men, 9 women, aged 25 to 80 years) with liver metastasis or hepatocellular carcinoma in the right hepatic lobe were examined with RT- and FB-DWI. In patients having multiple tumors, up to 3 lesions were selected by mutual agreement of 2 diagnostic radiologists. Finally, 59 nodules were selected for evaluation. Relative contrast ratio (RCR) between the lesions and surrounding parenchyma and ADC were measured in each hepatic lesion in each sequence. The differences in RCR and ADC between RT- and FB-DWI were statistically analyzed using Wilcoxon's signed rank test. The frequency of respiratory misregistration advents in each sequence was visually evaluated by the 2 diagnostic radiologists and assessed using McNemar's test. RESULTS: RCRs were significantly higher in RT- than in FB-DWI (P<0.001). The difference in ADC between the 2 sequences was not significant. However, ADCs tended to be more scattered in FB- than in RT-DWI. The frequency of respiratory misregistration advents was significantly higher in FB- than in RT-DWI. CONCLUSION: FB- was inferior to RT-DWI in both contrast between tumors and surrounding liver parenchyma and in accuracy of ADC measurement as far as the numbers of excitation in each sequence were the same. For preoperative examination of hepatic resection, RT- is more suitable than FB-DWI. |
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Authors:
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Katsuhiro Nasu; Yoshifumi Kuroki; Ryuzo Sekiguchi; Shigeru Nawano |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine Volume: 5 ISSN: 1347-3182 ISO Abbreviation: Magn Reson Med Sci Publication Date: 2006 Oct |
Date Detail:
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Created Date: 2006-12-01 Completed Date: 2007-03-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101153368 Medline TA: Magn Reson Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 129-36 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, National Cancer Center Hospital East, Chiba, Japan. kanasu@east.ncc.go.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Diffusion Magnetic Resonance Imaging / methods* Female Humans Liver / pathology* Liver Neoplasms / diagnosis*, secondary Male Middle Aged Respiration* |
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