Document Detail

The effect of salivary clearance of sucrose and fluoride on human dental plaque acidogenicity.
MedLine Citation:
PMID:  2282002     Owner:  NLM     Status:  MEDLINE    
Ten subjects rinsed with a 20% (0.58 M) sucrose solution with or without 0.2% NaF (905 parts/10(6) F-) added in two separate experiments. Saliva and plaque were collected before rinsing and after 2, 5, 10 and 30 min. Sucrose and fluoride concentrations in saliva and acid anion and fluoride concentrations in plaque were analysed. There was a statistically significant and positive correlation between the concentration of sucrose in the saliva 2 min after the rinse and the subsequent concentrations of lactate in plaque at 10 and 30 min after the rinse with sucrose alone but not in the presence of fluoride. Salivary fluoride concentrations during 2-30 min after the sucrose rinse were significantly correlated with plaque fluoride concentrations during the same time. The addition of fluoride to the sucrose rinse significantly inhibited lactate production.
A Oliveby; D A Weetman; D A Geddes; F Lagerlöf
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of oral biology     Volume:  35     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:  1990  
Date Detail:
Created Date:  1991-03-08     Completed Date:  1991-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  907-11     Citation Subset:  D; IM    
Department of Cariology, School of Dentistry, Karolinska Institute, Huddinge, Sweden.
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MeSH Terms
Acetates / analysis
Administration, Oral
Carboxylic Acids / analysis*
Dental Plaque / chemistry,  metabolism*
Fluorides / administration & dosage,  analysis,  metabolism*
Formates / analysis
Lactates / analysis
Propionates / analysis
Pyruvates / analysis
Saliva / chemistry,  metabolism*
Succinates / analysis
Sucrose / administration & dosage,  analysis,  metabolism*
Time Factors
Reg. No./Substance:
0/Acetates; 0/Carboxylic Acids; 0/Fluorides; 0/Formates; 0/Lactates; 0/Propionates; 0/Pyruvates; 0/Succinates; 57-50-1/Sucrose

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