Document Detail

The effect and safety after extended use of continuous negative pressure of 75 mmHg over mesh and allodermis graft on open sternal wound from oversized heart transplant in a 3-month-old infant.
MedLine Citation:
PMID:  20840183     Owner:  NLM     Status:  MEDLINE    
Negative pressure therapy (NPT) has been reported to be effective in treating infants with open chest wounds. This report further supports its effectiveness by treating a 3-month-old infant with a 12 × 7 cm sized opening in its chest after an oversized heart transplantation. After applying a mesh and allodermis over the defect, 75-mmHg continuous negative pressure was set and used for an extended period of 104 days. The haemodynamic status was evaluated during this period. The wound was closed with secondary intention and it healed well after NPT. There was no haemodynamic instability during the treatment course. The extended use of a continuous negative pressure of 75 mmHg over the mesh and alloderm graft was a reliable and safe option to close the massive defect in the chest of a 3-month-old infant.
Kangwoo Nathan Lee; Dong Man Seo; Joon Pio Hong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International wound journal     Volume:  7     ISSN:  1742-481X     ISO Abbreviation:  Int Wound J     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-15     Completed Date:  2011-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230907     Medline TA:  Int Wound J     Country:  England    
Other Details:
Languages:  eng     Pagination:  379-84     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. Journal Compilation © 2010 Blackwell Publishing Ltd and Inc.
Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
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MeSH Terms
Collagen / therapeutic use*
Heart Transplantation / methods*
Negative-Pressure Wound Therapy / methods*
Postoperative Care / methods*
Skin, Artificial
Sternotomy / adverse effects,  methods
Surgical Mesh
Time Factors
Reg. No./Substance:
0/Alloderm; 9007-34-5/Collagen

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