| The effect of riboflavin-ultraviolet A-induced collagen cross-linking on intraocular pressure measurement: an experimental study. | |
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MedLine Citation:
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PMID: 22467939 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To investigate the effect of corneal collagen cross-linking (CCL) on tonopen measurements of intraocular pressure (IOP). METHODS: CCL with 0.1% riboflavin solution and 30 min of ultraviolet A radiation was performed on the right eye of 15 New Zealand albino adult rabbits (1.8-2.4 kg) (15 eyes). The left eye served as control. IOP was measured by a pressure transducer system (true IOP) and by the tonopen hand-held device (corneal applanation tonometer) before treatment, at 1 week, 1 month and 3 months following CCL. Reference pressure in the globe was increased by increments of 10 mm Hg from 10 to 40 mm Hg, using an anterior chamber infusion on a stand with variable height, and tonopen IOP measurements were recorded for each reference pressure in both eyes. RESULTS: Before CCL, tonopen readings were similar between the two eyes (p>0.05). Tonopen underestimated the true IOP in all cases. Following CCL treatment, IOP measurements were significantly higher in the treated eye, at all time intervals (0.005<p<0.03). The most significant difference between true and measured IOP was noted at a reference pressure of 20 mm Hg. CONCLUSIONS: IOP measurements following CCL are overestimated by the tonopen, probably due to increased stiffness of the treated cornea. |
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Authors:
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Eitan Livny; Igor Kaiserman; Naama Hammel; Tami Livnat; David Zadok; Kremer Israel; Irit Bahar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-30 |
Journal Detail:
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Title: The British journal of ophthalmology Volume: - ISSN: 1468-2079 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-4-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Rabin Medical Center, Petah-Tiqva, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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