Document Detail

The effect of rheumatoid factor on the clearance of endogenous immune complexes formed in low-affinity mice during the induction of immune complex disease.
MedLine Citation:
PMID:  2953686     Owner:  NLM     Status:  MEDLINE    
Intravenous injection of rheumatoid factor (RF) had a marked effect on the clearance kinetics of immune complexes (IC) formed in vivo during induction of chronic immune complex disease in low-affinity mice. RF resulted in a significant increase in IC level and clearance time in 64% of mice with circulating IC after antigen injection, suggesting that RF may alter the handling of potentially pathogenic IC which localize in the renal capillaries causing glomerulonephritis.
M E Devey; D N Hogben
Related Documents :
9647206 - Requirements for b7-cd28 costimulation in mucosal iga responses: paradoxes observed in ...
12771426 - T helper responses to japanese encephalitis virus infection are dependent on the route ...
22019886 - Polymeric iga1 controls erythroblast proliferation and accelerates erythropoiesis recov...
22093256 - Postnatal growth defect in mice upon persistent hoxa2 expression in the chondrogenic ce...
20516636 - Skeletal phenotype of mice with a null mutation in cav 1.3 l-type calcium channel.
17394136 - A new murine model to define the critical pathologic and therapeutic mediators of polym...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  83     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-07-15     Completed Date:  1987-07-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  206-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antibody Affinity
Antigen-Antibody Complex / immunology*
Immune Complex Diseases / immunology*
Metabolic Clearance Rate
Rheumatoid Factor / immunology*
Reg. No./Substance:
0/Antigen-Antibody Complex; 9009-79-4/Rheumatoid Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  T cell activation surface markers and autologous mixed lymphocyte reaction do not differ in true and...
Next Document:  Influence of some dietary chemopreventive agents on the expression of functional differentiation of ...