Document Detail

The effect of revascularisation of an ischaemic lower limb on leukotriene E4 production.
MedLine Citation:
PMID:  11427036     Owner:  NLM     Status:  MEDLINE    
It has previously been shown that leukotriene E4 production is increased both in acute and chronic lower limb ischaemia. The aim of this study was to measure the effect of revascularisation on leuktriene E4 excretion in chronic lower limb ischaemia. Revascularisation did not affect significantly on leukotriene E4 excretion (preop. 34.9+/-7.1 pg/mg creatinine, postop. 24.5+/-4.7 pg/mg creatinine, n=10, P<0.238). We suggest that the enhanced leukotriene E4 production continues after revascularisation which may have a therapeutical implication.
P Rossi; P Kuukasjärvi; J P Salenius; A Riutta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prostaglandins, leukotrienes, and essential fatty acids     Volume:  64     ISSN:  0952-3278     ISO Abbreviation:  Prostaglandins Leukot. Essent. Fatty Acids     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-27     Completed Date:  2001-12-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8802730     Medline TA:  Prostaglandins Leukot Essent Fatty Acids     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  289-90     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Harcourt Publishers Ltd.
Department of Surgery, Central Hospital of Central Finland, FIN-40600 Jyväskylä, Finland.
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MeSH Terms
Chronic Disease
Ischemia / metabolism*,  surgery
Leg / blood supply,  pathology
Leukotriene E4 / biosynthesis*,  urine
Middle Aged
Muscle, Skeletal / blood supply
Vascular Surgical Procedures*
Reg. No./Substance:
75715-89-8/Leukotriene E4

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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