Document Detail


The effect of resistance training on muscle strength and physical function in older, postmenopausal breast cancer survivors: a randomized controlled trial.
MedLine Citation:
PMID:  22193780     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Older breast cancer survivors (BCS) report more falls and functional limitations than women with no cancer history. Exercise training could reduce risk factors for future falls and disability.
METHODS: We conducted a randomized, controlled trial in 106 early-stage, postmenopausal BCS who were ≥50 years old at diagnosis and post-treatment. Women were randomly assigned to a 1-year resistance + impact exercise program or a stretching placebo program. Endpoints were one repetition maximum bench press and leg press strength, timed five chair stands, 4 m usual walk speed, timed stance tests, handgrip strength, self-report physical function, and fatigue. We also examined the influence of age, adjuvant hormone therapy use, and exercise adherence on study outcomes.
RESULTS: Women in the resistance + impact training program significantly improved maximal leg (p <0 .02) and bench (p <0 .02) press strength compared to the stretching group. Women who attended 50% or more of prescribed resistance training sessions had significantly better changes in maximal strength measures compared to less adherent women.
CONCLUSIONS: Resistance + impact exercise is superior to stretching at improving maximal muscle strength and exercise adherence contributes to the degree of improvement.
IMPLICATIONS FOR CANCER SURVIVORS: Older BCS can safely engage in resistance exercise that improves lower and upper body strength, thereby reducing a risk factor for falls and future disability. However, the ability of resistance training to shift other indices of fall and disability risk, i.e., balance and function, is unclear. Strategies to promote adherence to resistance training could lead to greater improvements in strength.
Authors:
Kerri M Winters-Stone; Jessica Dobek; Jill A Bennett; Lillian M Nail; Michael C Leo; Anna Schwartz
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2011-12-23
Journal Detail:
Title:  Journal of cancer survivorship : research and practice     Volume:  6     ISSN:  1932-2267     ISO Abbreviation:  J Cancer Surviv     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-04-09     Completed Date:  2012-08-28     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101307557     Medline TA:  J Cancer Surviv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  189-99     Citation Subset:  IM    
Affiliation:
School of Nursing, Oregon Health and Science University, 3455 SW US Veteran's Hospital Rd, Mailcode: SN-ORD, Portland, OR 97239, USA. wintersk@ohsu.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Breast Neoplasms / therapy*
Exercise Therapy*
Female
Hand Strength / physiology*
Humans
Middle Aged
Muscle Strength / physiology*
Neoplasm Staging
Postmenopause*
Prognosis
Resistance Training*
Single-Blind Method
Survivors*
Grant Support
ID/Acronym/Agency:
1R01 CA120123/CA/NCI NIH HHS; UL1 RR024140/RR/NCRR NIH HHS; UL1 TR000128/TR/NCATS NIH HHS
Comments/Corrections

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