Document Detail

The effect of repeat exercise on pulmonary diffusing capacity and EIH in trained athletes.
MedLine Citation:
PMID:  9927016     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of this study was to determine the effects of repeated heavy exercise on postexercise pulmonary diffusing capacity (DL) and the development of exercise induced arterial hypoxemia (EIH). METHODS: 13 endurance-trained, male athletes (age = 27+/-3 yr, height = 179.6+/-5.0 cm, weight = 71.8+/-6.9 kg, VO2max = 67.0+/-3.6 mL x kg(-1) x min(-1) performed two consecutive, continuous exercise tests on a cycle ergometer to VO2max, separated by 60 min of recovery. Arterial oxygen saturation (%SaO2) was measured via ear oximetry, and resting DL was measured and partitioned by the single-breath method, before exercise and 60 min after each exercise bout. RESULTS: No significant differences resulted in VO2max, VE, peak heart rate (HR), or breathing frequency between exercise bouts (P > 0.05). There was a small but significant decrease (454-446 W; P < 0.05) in peak power output in the second test. %SaO2 decreased from resting values during both exercise tasks, but there was no difference between the minimum saturation achieved in test 1 (91.4) or test 2 (91.6; P > 0.05). After the initial exercise bout, significant decreases (P < 0.05) occurred in DL (11%), membrane diffusing capacity (DM) (11%) and pulmonary capillary volume (VC) (10%). Further decreases occurred in DL (6%; P < 0.05), DM (2%; P > 0.05), and VC (10%; P < 0.05) after the second exercise bout. CONCLUSIONS: These observations question the meaning of post exercise measurements of pulmonary diffusion capacity, and its components, relative to pulmonary gas exchange and pulmonary fluid accumulation during exercise. The fact that there was no further change in %SaO2 after the second test suggests that if any interstitial edema developed, it was of no clinical significance; alternatively, the changes in DL(CO) may be related more to redistribution of blood than the development of pulmonary edema.
D C McKenzie; I L Lama; J E Potts; A W Sheel; K D Coutts
Related Documents :
9309996 - Nitric oxide inhalation during exercise in chronic obstructive pulmonary disease.
1184646 - Excessive thoracic lordosis and loss of pulmonary function in patients with idiopathic ...
15846646 - Prostacyclin for pulmonary hypertension in adults.
3253396 - Chiropractic management of chronic obstructive pulmonary disease.
16143716 - Perturbed reproductive development in salt-treated sorghum bicolor: a consequence of mo...
10326316 - Camp superteens. an asthma education program for adolescents.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  31     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-03-23     Completed Date:  1999-03-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  99-104     Citation Subset:  IM; S    
Allan McGavin Sports Medicine Centre and the School of Human Kinetics, The University of British Columbia, Vancouver, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anoxia / physiopathology
Exercise / physiology*
Exercise Test
Lung / physiology
Oxygen / analysis*
Physical Endurance / physiology*
Pulmonary Diffusing Capacity / physiology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Muscle oxygenation trends during constant work rate cycle exercise in men and women.
Next Document:  Does exercise intensity or diet influence lactic acid accumulation in breast milk?