Document Detail

The effect of pure right ventricular ischemia on right and left ventricular performance in the anesthetized dog.
MedLine Citation:
PMID:  8261489     Owner:  NLM     Status:  MEDLINE    
This study was planned to investigate the effect of ischemic dysfunction of the free wall of the right ventricle on right and left ventricular performance in the presence of a normally contracting interventricular septum. The experiments were performed in 6 anesthetized dogs in which echocardiogram, electrocardiogram, aortic blood pressure and left and right ventricular pressure were recorded. In the dog, the contractility of the septum is not affected by the occlusion of the right coronary artery which does not perfuse this part of the myocardium. Complete occlusion of the major individual ventricular branches and partial occlusion of the main right coronary artery did not impair right ventricular performance. Only complete occlusion of the main artery affected right and left ventricular function as revealed by echocardiogram. Reduced output by the ischemic right ventricle caused a reduction in left ventricular diastolic and systolic dimensions and in left ventricular developed pressure without any effect on left ventricular end-diastolic pressure.
D Gattullo; D Casalucci; L Gastaldi; M Morello; P Pagliaro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  83     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1993  
Date Detail:
Created Date:  1994-01-27     Completed Date:  1994-01-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  61-70     Citation Subset:  IM    
Dipartimento di Anatomia e Fisiologia Umana, Università di Torino, Italia.
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MeSH Terms
Coronary Disease / pathology,  physiopathology*,  ultrasonography
Heart Septum / pathology
Heart Ventricles / pathology
Hemodynamics / physiology
Myocardial Ischemia / pathology,  physiopathology*,  ultrasonography
Ventricular Function, Left / physiology*
Ventricular Function, Right / physiology*

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