Document Detail

The effect on psoriasis of clobetasol propionate used alone or in combination with UVB.
MedLine Citation:
PMID:  6203304     Owner:  NLM     Status:  MEDLINE    
A study has been carried out to compare the effect of a combination of clobetasol propionate and UVB versus placebo/UVB. No significant reduction in time to healing was observed. However, symptoms abated more rapidly in the steroid/UVB group. Recurrences occurred at an earlier stage following the steroid UVB combination for long periods. A third group, treated solely with clobetasol propionate has also been investigated, but results were poorer than those described above. It is concluded that steroids in combination with UVB should be used only during the initial period in order to achieve a more rapid alleviation of symptoms and to avoid the side effects.
O Larkö; G Swanbeck; H Svartholm
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Publication Detail:
Type:  Case Reports; Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  64     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1984  
Date Detail:
Created Date:  1984-07-09     Completed Date:  1984-07-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  151-4     Citation Subset:  IM    
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MeSH Terms
Betamethasone / analogs & derivatives*
Clinical Trials as Topic
Clobetasol / analogs & derivatives*,  therapeutic use
Double-Blind Method
Psoriasis / drug therapy*
Time Factors
Ultraviolet Therapy / methods*
Reg. No./Substance:
25122-41-2/Clobetasol; 378-44-9/Betamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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