| The effect of protamine on proteinuria and glomerular sclerosis in aminonucleoside nephropathy. | |
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MedLine Citation:
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PMID: 7101279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An administration of protamine sulfate combined with aminonucleoside of puromycin (AN) could produce in rats severe nephrotic syndrome and histological changes similar to focal glomerular sclerosis more distinctly than AN alone. This may be attributed to the action of protamine which seemed to enhance the effect of AN, causing polyanion loss at the glomerular basement membrane. |
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Authors:
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T Saito; K Yamakage; K Kurosawa; Y Kyogoku; T Furuyama; K Yoshinaga |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Tohoku journal of experimental medicine Volume: 136 ISSN: 0040-8727 ISO Abbreviation: Tohoku J. Exp. Med. Publication Date: 1982 Apr |
Date Detail:
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Created Date: 1982-09-24 Completed Date: 1982-09-24 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0417355 Medline TA: Tohoku J Exp Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 461-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Kidney Glomerulus / drug effects, pathology* Male Nephrotic Syndrome / chemically induced, pathology* Protamines / pharmacology* Proteinuria* Puromycin / analogs & derivatives* Puromycin Aminonucleoside / toxicity* Rats Rats, Inbred Strains Sclerosis |
| Chemical | |
Reg. No./Substance:
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0/Protamines; 53-79-2/Puromycin; 58-60-6/Puromycin Aminonucleoside |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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