Document Detail

The effect of prolonged rupture of membranes on circulating neonatal nucleated red blood cells.
MedLine Citation:
PMID:  16222345     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES:To test the hypothesis that absolute nucleated red blood cells (ANRBC) counts are higher at birth in infants who were born after prolonged rupture of membranes (PROM, >24 hours).STUDY DESIGN:Retrospective study of 31 infants admitted to the neonatal intensive care unit who were born after PROM, and pair matched for gestational age and Apgar scores with 31 no PROM controls. Venous ANRBC counts were obtained within 1 hour of life. RESULTS:Groups did not differ in birthweight, gestational age, Apgar scores, and platelets counts. The ANRBC counts and hematocrit were significantly higher in infants who were born after PROM than in controls. CONCLUSIONS:Infants born after PROM have higher ANRBC counts at birth than control infants. We suggest that increased fetal erythropoiesis exists in infants who are delivered after PROM. If correct, our interpretation supports the theory that fetal hypoxia and/or ischemia may result from PROM.
Dror Mandel; Tal Oron; Galit Sheffer Mimouni; Yoav Littner; Shaul Dollberg; Francis B Mimouni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  25     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-27     Completed Date:  2006-01-17     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  690-3     Citation Subset:  IM    
Copyright Information:
Journal of Perinatology (2005) 25, 690-693. doi:10.1038/; published online 13 October 2005.
Department of Neonatology, Tel Aviv-Sourasky Medical Center, Tel Aviv, Israel.
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MeSH Terms
Apgar Score
Blood Cell Count
Erythropoiesis* / physiology
Fetal Membranes, Premature Rupture / physiopathology*
Fetus / physiology*
Gestational Age
Infant, Newborn
Time Factors

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