Document Detail

The effect of profiling dialysate sodium and ultrafiltration on patient comfort and cardiovascular stability during haemodialysis.
MedLine Citation:
PMID:  14598948     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to investigate what affect profiling dialysate sodium and ultrafiltration rate had on cardiovascular stability during haemodialysis, and if there was any effect on patients' fluid balance, thirst, serum sodium levels, blood pressure, or comfort and tolerance. The past decade has seen major advances in haemodialysis machine technology. Parallel developments have included profiling dialysate sodium levels and fluid removal during dialysis. However, some dialysis centres do not use profiling due to fears of long-term detrimental effects, especially with regard to hypertension and fluid control. Within my own workplace, approximately 30% of haemodialysis treatments utilise either sodium or ultrafiltration profiling, or a combination of both. Anecdotally, we have seen an increase in cardiovascular stability and haemodialysis tolerance. The aim of this study was to identify the effects of profiling haemodialysis, to ensure that the treatment we offer patients is safe and effective.
M Gerrish; J Little
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  EDTNA/ERCA journal (English ed.)     Volume:  29     ISSN:  1019-083X     ISO Abbreviation:  EDTNA ERCA J     Publication Date:    2003 Apr-Jun
Date Detail:
Created Date:  2003-11-05     Completed Date:  2003-12-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9805754     Medline TA:  EDTNA ERCA J     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  61, 65-6, 68-70 passim     Citation Subset:  N    
Lincoln Renal Unit, University Hospitals of Leicester NHS Trust, Lincoln, UK.
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MeSH Terms
Analysis of Variance
Attitude to Health
Cardiovascular System / drug effects*,  physiopathology
Cross-Over Studies
Hemodialysis Solutions / chemistry,  pharmacology*
Hypotension / etiology
Kidney Failure, Chronic / metabolism,  physiopathology,  psychology,  therapy*
Monitoring, Physiologic / methods*
Pain / etiology,  prevention & control
Renal Dialysis / adverse effects,  methods*
Sodium / analysis,  blood,  pharmacology*
Thirst / drug effects
Water-Electrolyte Imbalance / etiology
Weight Gain / drug effects
Reg. No./Substance:
0/Hemodialysis Solutions; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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