Document Detail

The effect of prior radiation therapy for treatment of nasopharyngeal cancer on wound healing following extractions: incidence of complications and risk factors.
MedLine Citation:
PMID:  17222536     Owner:  NLM     Status:  MEDLINE    
This is a prospective study of wound healing after extractions in patients who had radiation therapy for nasopharyngeal cancer. From 40 patients who fulfilled all the study criteria were extracted a total of 155 teeth. The demographic data were analysed, checking for factors that might affect the healing process after extraction. Wound healing was divided into three groups: normal wound healing, delayed healing and osteoradionecrosis. Logistic regression was used to analyse possible relationships. There was a low complication rate: 5.8% and 1.9% of extractions showed delayed healing and osteoradionecrosis, respectively. The age of the patient at time of extraction was the only significant factor that influenced the occurrence of delayed healing. It was observed that localized radiation absorption was considerably different from the total radiation dose. In conclusion, postradiation extractions have a low risk of complications and the results point to age as a factor that may influence wound healing.
K W Lye; J Wee; F Gao; P S H Neo; Y L Soong; C Y Poon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-01-10
Journal Detail:
Title:  International journal of oral and maxillofacial surgery     Volume:  36     ISSN:  0901-5027     ISO Abbreviation:  Int J Oral Maxillofac Surg     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-02-26     Completed Date:  2007-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8605826     Medline TA:  Int J Oral Maxillofac Surg     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  D; IM    
Department of Oral & Maxillofacial Surgery, National Dental Centre, Singapore.
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MeSH Terms
Age Factors
Dental Arch / radiation effects
Epithelium / radiation effects
Follow-Up Studies
Middle Aged
Nasopharyngeal Neoplasms / radiotherapy*
Osteoradionecrosis / etiology
Prospective Studies
Radiotherapy / adverse effects
Radiotherapy Dosage
Risk Factors
Time Factors
Tooth / radiation effects
Tooth Extraction*
Tooth Socket / radiation effects*
Treatment Outcome
Wound Healing / radiation effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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