Document Detail

The effect of premarin on blood loss attending open heart surgery.
MedLine Citation:
PMID:  177145     Owner:  NLM     Status:  MEDLINE    
Premarin was administered prophylactically to every other patient in a series of 148 consecutive cases of open intracardiac surgery. Of these, 132 patients were matched to analyse the results of Premarin administration and postoperative blood loss. There were 67 patients who were given Premarin and 65 who did not receive this drug; both groups were identical in respect of age and sex. Matching was undertaken according to history of previous cardiac operations and anticoagulation, type of valve surgery or repair of congenital anomaly, duration of perfusion, platelet count and the use of fresh blood and epsilon-aminocaproic acid in the postoperative period. The prophylactic use of Premarin was not associated with a reduction in postoperative bleeding.
D A Mary; A Abid; P Pohlner; T Y Kang; R Meszaros; M I Ionescu
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  63     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  196-8     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiac Surgical Procedures*
Clinical Trials as Topic
Estrogens, Conjugated (USP) / therapeutic use*
Heart Defects, Congenital / surgery
Hemorrhage / prevention & control*
Middle Aged
Postoperative Complications / prevention & control*
Reg. No./Substance:
0/Estrogens, Conjugated (USP)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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