Document Detail


The effect of pregnancy on echocardiographic variables in healthy bitches.
MedLine Citation:
PMID:  20615775     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Little is known of the effect of pregnancy on canine cardiovascular function. This study was undertaken to evaluate the effect of pregnancy on canine echocardiographic variables.
ANIMALS, MATERIALS AND METHODS: Serial echocardiographic examinations of 7 healthy, sexually intact female canine mongrels dogs that weighed between 9.7 and 13.4 kg were performed. The subjects were examined prior to ovulation, during early pregnancy, during late pregnancy within 6 days of parturition and again, after puppies were weaned.
RESULTS: Repeated measures ANOVA disclosed a statistically significant effect of time on end-systolic left ventricular dimension (LVIDs, p=0.005), left ventricular fractional shortening (%FS, p=0.001), Doppler-derived inflow and ejection velocities (all p<0.05), as well as on heart rate (HR, p=0.03). %FS, HR, aortic ejection velocity, pulmonic ejection velocity and early diastolic mitral inflow velocity were maximal during late pregnancy. The increase in %FS resulted from a decrease in LVIDs. For Doppler-derived flow velocities, the range of differences of least square means (m/s) between early and late pregnancy was 0.21-0.32.
CONCLUSIONS: While the magnitude of effect generally was small, this study provides evidence that pregnancy in healthy bitches is associated with changes in echocardiographic variables.
Authors:
Jonathan A Abbott
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-07
Journal Detail:
Title:  Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology     Volume:  12     ISSN:  1875-0834     ISO Abbreviation:  J Vet Cardiol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-20     Completed Date:  2010-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101163270     Medline TA:  J Vet Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  123-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier B.V. All rights reserved.
Affiliation:
Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Duck Pond Drive, Blacksburg, VA 24061-0442, USA. abbottj@vt.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs / anatomy & histology,  physiology*
Echocardiography / veterinary*
Female
Heart Ventricles / anatomy & histology,  ultrasonography
Longitudinal Studies
Pregnancy
Pregnancy, Animal / physiology*
Reference Values
Ventricular Function / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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