Document Detail

The effect of pre-exercise diesel exhaust exposure on cycling performance and cardio-respiratory variables.
MedLine Citation:
PMID:  23033992     Owner:  NLM     Status:  In-Data-Review    
Purpose: To determine the effect of pre-exercise exposure to diesel exhaust (DE) on 20-km cycling performance, pulmonary function, and cardio-respiratory variables during exercise. Methods: Eight endurance-trained males participated in the study. Test days consisted of a 60-min exposure to either filtered air (FA) or DE, followed by a 20 km cycling time trial. Exposures to DE were at a concentration of 300 µg/m(3) of PM(2.5). Forced expiratory volume in 1 s (FEV(1)) and forced vital capacity (FVC) were measured before and after exposure, and after exercise. Oxygen consumption (VO(2)) and carbon dioxide production (VCO(2)), minute ventilation (V(E)), tidal volume (V(T)), breathing frequency (F(B)), heart rate and oxyhemoglobin saturation (SpO(2)), were collected during the time trials. The effect of condition on time trial duration, an order effect, and mean cardio-respiratory variables were each analysed using paired T-tests. Repeated-measures ANOVA were used to assess the effect of DE exposure on pulmonary function. Results: There was a main effect of condition (FA vs. DE) on the change in FEV(1) from baseline, and in exercise heart rate. Post hoc tests revealed that exercise-induced bronchodilation was significantly attenuated following DE compared to FA. There were no main effects of condition on 20 km cycling performance, or VO(2), VCO(2), V(E), V(T), F(B) and SpO(2) during a 20 km time trial. Conclusion: A 60-min exposure to DE prior to exercise significantly attenuated exercise-induced bronchodilation and significantly increased heart rate during exercise. Pre-exercise exposure to diesel exhaust did not significantly impair 20 km cycling time trial performance.
Luisa V Giles; Christopher Carlsten; Michael S Koehle
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Inhalation toxicology     Volume:  24     ISSN:  1091-7691     ISO Abbreviation:  Inhal Toxicol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8910739     Medline TA:  Inhal Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  783-9     Citation Subset:  IM    
School of Kinesiology, University of British Columbia , British Columbia , Canada.
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