Document Detail

The effect of povidone-iodine on thyroid function of neonates with different birth sizes.
MedLine Citation:
PMID:  9926509     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to elucidate the role of povidone-iodine (PV-I) on thyroid function of newborns with different birth sizes in a high iodine-intake city. Serial measurements of serum thyroxine (T4) and thyrotropin (TSH) levels were done in 44 newborns locally treated with 10% PV-I for insertion of percutaneous central venous catheters. The results showed that the thyroid function was influenced prominently in very-low-birth weight (VLBW) babies. TSH went significantly higher after application of PV-I for 48 hours in VLBW babies. The smaller the babies were, the lower the T4 at birth and thereafter. In conclusion, PV-I is suggested to be avoided for single application on a wide skin surface in VLBW babies, even in an area with high iodine-intake population.
M J Jeng; C Y Lin; W J Soong; K J Hsiao; B Hwang; S H Chiang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui     Volume:  39     ISSN:  0001-6578     ISO Abbreviation:  Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  1999-02-18     Completed Date:  1999-02-18     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  16210470R     Medline TA:  Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  371-5     Citation Subset:  IM    
Department of Pediatrics, Veterans General Hospital-Taipei, Taiwan.
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MeSH Terms
Anti-Infective Agents, Local / pharmacology*
Birth Weight*
Infant, Newborn / physiology*
Infant, Very Low Birth Weight
Povidone-Iodine / pharmacology*
Thyroid Gland / drug effects*,  physiology
Thyrotropin / blood
Thyroxine / blood
Reg. No./Substance:
0/Anti-Infective Agents, Local; 25655-41-8/Povidone-Iodine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin

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