Document Detail

The effect of postural changes (leg lifting) on tissue Doppler parameters in coronary artery disease.
MedLine Citation:
PMID:  18497554     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: We investigated the effect of increased preload through postural changes (leg lifting) on tissue Doppler parameters in patients with and without coronary artery disease (CAD). STUDY DESIGN: The study included 42 patients who were scheduled for coronary angiography. All the patients underwent standard two-dimensional, color Doppler and tissue Doppler echocardiography before coronary angiography. Tissue Doppler imaging was performed from septal and lateral mitral annuluses at baseline and during 45 degrees leg lifting followed by two-minute stabilization. Patients were grouped based on coronary angiography findings: those having stenosis greater than 70% were considered to have CAD and those with normal coronary arteries comprised the control group. Echocardiography measurements were compared between the two groups. RESULTS: Angiography showed normal coronary arteries or border irregularities in 22 patients and CAD in 20 patients. The two groups were similar with regard to demographic data and ejection fractions, except for male preponderance in the CAD group. Compared with the control group, patients with CAD exhibited a significantly lower isovolumic acceleration rate (IVA) at the lateral (p=0.007) and septal (p=0.03) mitral annuluses. In the control group, leg lifting resulted in increased systolic velocity (S) compared with baseline at the lateral (p=0.009) and septal (p=0.01) annuluses, whereas S wave augmentation was only significant at the septal annulus (p=0.009) in patients with CAD. No significant change was observed in IVA following leg lifting in both groups. CONCLUSION: Preload alteration induced by leg lifting resulted in similar changes in tissue Doppler parameters in patients with and without CAD, except for blunted augmentation of S wave at the lateral annulus in CAD. Detection of decreased IVA at baseline may be a useful finding for CAD.
Bahar Pirat; Aylin Yildirir; Vahide Simşek; Bülent Ozin; Haldun Müderrisoğlu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır     Volume:  36     ISSN:  1016-5169     ISO Abbreviation:  Turk Kardiyol Dern Ars     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-05-23     Completed Date:  2008-08-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426239     Medline TA:  Turk Kardiyol Dern Ars     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  96-102     Citation Subset:  IM    
Department of Cardiology, Başkent University Faculty of Medicine, Ankara, Turkey.
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MeSH Terms
Blood Flow Velocity
Case-Control Studies
Coronary Angiography
Coronary Artery Disease / physiopathology*,  radiography,  ultrasonography
Echocardiography, Transesophageal
Leg / blood supply*
Middle Aged
Mitral Valve / physiology*,  ultrasonography
Posture / physiology*
Regional Blood Flow
Ultrasonography, Doppler
Ventricular Dysfunction, Left / physiopathology*,  radiography,  ultrasonography

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