Document Detail

The effect of pilocarpine on electrodermal resistance in chronic hemodialyzed patients.
MedLine Citation:
PMID:  8448923     Owner:  NLM     Status:  MEDLINE    
Electric resistance of forearm skin was examined in 40 hemodialyzed (HD) patients under resting conditions and after subjecting the skin to the action of a 10% pilocarpine gel. The results were compared with a control group of a 100 healthy volunteers. An increased skin resistance was observed before dialysis and then a significant post-dialysis fall to the normal level followed. The response to the applied pharmacological stimulus in the HD group was similar to that in the control group. The results suggest that the rise in skin resistance in patients with renal failure and the so-called uremic dry skin, are not connected with the dysfunction of the glands themselves but rather with their insufficient stimulation.
K Marczewski; L Janicka; J Cudny
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  39     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-04-09     Completed Date:  1993-04-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  88-91     Citation Subset:  IM    
Clinic of Nephrology, Medical Academy, Lublin, Poland.
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MeSH Terms
Galvanic Skin Response / drug effects*
Kidney Failure, Chronic / complications,  physiopathology*,  therapy
Pilocarpine / diagnostic use*
Renal Dialysis*
Skin Diseases / etiology,  physiopathology
Sweat Glands / drug effects,  physiopathology*
Sweating / physiology
Reg. No./Substance:

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