| The effect of a physiological concentration of caffeine on the endurance of maximally and submaximally stimulated mouse soleus muscle. | |
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MedLine Citation:
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PMID: 23292763 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The use of caffeine as an ergogenic aid to promote endurance has been widely studied, with human literature showing the greatest benefit during submaximal muscle activities. Recent evidence suggests that the acute treatment of skeletal muscle with physiological concentrations of caffeine (70 μM maximum) will directly potentiate force production. The aims of the present study are: firstly, to assess the effects of a physiological concentration (70 μM) of caffeine on endurance in maximally activated mouse soleus (relatively slow) muscle; and secondly, to examine whether endurance changes when muscle is activated submaximally during caffeine treatment. Maximally stimulated soleus muscle treated with 70 μM caffeine resulted in a significant (17.6 %) decrease in endurance. In contrast, at a submaximal stimulation frequency, caffeine treatment significantly prolonged endurance (by 19.2 %). Findings are activation-dependent such that, during high frequency stimulation, caffeine accelerates fatigue, whereas, during low frequency stimulation, caffeine delays fatigue. |
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Authors:
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Jason Tallis; Rob S James; Val M Cox; Michael J Duncan |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-6 |
Journal Detail:
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Title: The journal of physiological sciences : JPS Volume: - ISSN: 1880-6562 ISO Abbreviation: J Physiol Sci Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101262417 Medline TA: J Physiol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Faculty of Health and Life Sciences, James Starley Building, Coventry University, Priory Street, Coventry, CV1 5FB, UK, tallisj2@uni.coventry.ac.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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