| The effect of physical training in chronic heart failure. | |
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MedLine Citation:
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PMID: 16194620 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chronic heart failure (CHF). The aim of our study was to evaluate the outcome of supervised physical training on CHF patients by measuring both central and peripheral factors. METHODS: This was a prospective randomized study, including 43 patients with CHF, New York Heart Association (NYHA) class II or III, mean age 68 years. After initial measurements of VO2 peak, 6 min walk distance, muscle strength, plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), echocardiogram, measurements of pulmonary function and quality of life questionnaire, patients were randomized to either a training group (n = 21) or a control group (n = 22). The training group had supervised aerobic and resistance training program twice a week for five months. After the training program was completed, all measurements were repeated in both groups. RESULTS: No training related adverse events were reported. Significant improvement was found between groups in the six minute walk test (+37.1 m vs. +5.3 m, p = 0.01), work load on the bicycle exercise test (+6.1 W vs. +2.1 W, p = 0.03), time on the bicycle exercise test (+41 s vs. +0 s, p = 0.02) and quadriceps muscle strength test (+2.8 kg. vs. +0.2 kg., p = 0.003). Quality of life factors that reflect exercise tolerance and general health, improved significantly in the training group compared to the control group. No other significant changes were found between the two groups. CONCLUSION: Supervised physical training as used in this study appears safe for CHF patients in NYHA class II or III. The improvement in functional capacity observed in the training group seems to be related to peripheral factors rather than in central cardiovascular performance. |
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Authors:
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Sólrún Jónsdóttir; Karl K Andersen; Axel F Sigurosson; Stefán B Sigurosson |
Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2005-09-27 |
Journal Detail:
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Title: European journal of heart failure Volume: 8 ISSN: 1388-9842 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2006-01-02 Completed Date: 2006-04-18 Revised Date: 2011-06-08 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 97-101 Citation Subset: IM |
Affiliation:
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Landspitali-University Hospital, Department of Physical Therapy, Reykjavik, Iceland. solval@simnet.is |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atrial Natriuretic Factor / blood Exercise Therapy* Exercise Tolerance / physiology* Female Follow-Up Studies Heart Failure / blood, physiopathology, therapy* Humans Male Natriuretic Peptide, Brain / blood Oxygen Consumption / physiology Prospective Studies Quality of Life Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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114471-18-0/Natriuretic Peptide, Brain; 85637-73-6/Atrial Natriuretic Factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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