Document Detail

The effect of pessaries on the vaginal microenvironment.
MedLine Citation:
PMID:  25046810     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate differences in vaginal culture, microscopy and gram stain between postmenopausal women who wear pessaries and those who do not in order to explain pessary-related, bothersome vaginal discharge.
STUDY DESIGN: Postmenopausal women not using exogenous estrogen who had either been wearing a pessary for at least 3 months or who were undergoing their first pessary fittings were approached for enrollment. Symptoms were assessed, and vaginal fluid was collected for culture, microscopy, and gram stain. A cross-sectional analysis was performed, comparing the new and return pessary wearers. The new pessary users were also sampled at 2 weeks, 3 months, and 6 months after fitting.
RESULTS: Women who wore pessaries were more likely to be bothered by discharge (30.0% vs. 2.1%, p<0.001). They were also more likely to show microscopic evidence of vaginal inflammation and vaginitis. Prospective data showed that these changes developed during the first 2 weeks of pessary use. Aerobic and anaerobic organisms were nearly identical in women with and without in the cross-sectional analysis and at all time points in the prospective analysis.
CONCLUSION: Pessary-related, bothersome vaginal discharge develops early and may be due to an inflammatory process in the vagina.
Sarah Collins; Richard Beigi; Colleen Mellen; David O'sullivan; Paul Tulikangas
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-18
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  -     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Mosby, Inc. All rights reserved.
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